Superfund Research Program

Immunoassays for Human and Environmental Health Monitoring

Project Leader: Bruce D. Hammock
Grant Number: P42ES004699
Funding Period: 1995-2023

Project-Specific Links

Publications

2024

• Abdalla HB, Puhl L, Rivas CA, Wu Y, Rojas P, Trindade da Silva CA, Hammock BD, Maddipati KR, Soares MQ, Clemente-Napimoga JT, Kantarci A, Napimoga MH, Van Dyke TE. 2024. Modulating the sEH/EETs axis restrains specialized proresolving mediator impairment and regulates T cell imbalance in experimental periodontitis. J Immunol 212(3):433-445. doi:10.4049/jimmunol.2300650 PMID:38117781
• Chen Y, Jianwen S, Tong H, Wang J, Ruolin C, Xu H, Chen L, Morisseau C, Zhang M, Shi Y, Han C, Zhuang J, Jing Y, Liu Z, Hammock BG, Chen G. 2024. Design and synthesis of dual-targeting inhibitors of sEH and HDAC6 for the treatment of neuropathic pain and lipopolysaccharide-induced mortality. J Med Chem 67(3):2095-2117. doi:10.1021/acs.jmedchem.3c02006 PMID:38236416
• Deng W, Wang D, Dai P, Hong Y, Xiong J, Duan L, Lu R, Wan J, Du H, Hammock BG, Yang W. 2024. Development of a sensitive direct competitive chemiluminescent enzyme immunoassay for gentamicin based on the construction of a specific single-chain variable fragment-alkaline phosphatase fusion protein. Microchemical Journal 197:doi:10.1016/j.microc.2023.109706 PMID:38283367 PMCID:10810264
• Fang X, Liu T, Xue C, Xue G, Wu M, Liu P, Hammock BD, Lai W, Peng J, Zhang C. 2024. Competitive ratiometric fluorescent lateral flow immunoassay based on dual emission signal for sensitive detection of chlorothalonil. Food Chem 433:137200. doi:10.1016/j.foodchem.2023.137200 PMID:37678117
• Gao Q, Chen L, An Z, Wang Y, Yang D, Wang Z, Kang J, Barnych B, Hammock BD, Huo J, Zhang J. 2024. Development of an immunoassay based on a specific antibody for the detection of diphenyl ether herbicide fomesafen. Sci Total Environ 914:169858. doi:10.1016/j.scitotenv.2023.169858 PMID:38190900
• Gao S, Abd El-Aty AM, Xu L, Zhao J, Li J, Lei X, Zhao Y, She Y, Jin F, Wang J, Yuan S, Jin M, Zheng L, Hammock BD. 2024. Rapid detection of prometryn residues in agricultural samples: Method comparison of the ic-ELISA and colloidal gold immunochromatographic test strips. ACS Agric Sci Technol doi:10.1021/acsagscitech.3c00490
• Kelly A, Wang W, Rothenberger E, Yang J, Gilligan MM, Kipper FC, Attaya A, Gartung A, Hwang SH, Gillespie M, Bayer R, Quinlivan K, Torres K, Huang S, Mitsiades N, Yang H, Hammock BD, Panigrahy D. 2024. Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase. Proc Natl Acad Sci U S A 121(7):doi:10.1073/pnas.2314085121 PMID:38330013
• Li P, Abd El-Aty AM, Jiang H, Shen J, Wang Z, Wen K, Li J, Wang S, Wang J, Hammock BD, Jin M. 2024. Immunoassays and emerging analytical techniques of fipronil and its metabolites for food safety: A review. J Agric Food Chem 72(4):2059-2076. doi:10.1021/acs.jafc.3c07428 PMID:38252458
• Naeem Z, Zukunft S, Huard A, Hu J, Hammock BD, Weigert A, Frömel T, Fleming I. 2024. Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to inflammatory stimuli. Biomed Pharmacother 171:116127. doi:10.1016/j.biopha.2024.116127 PMID:38198951 PMCID:10857809
• Trindade-da-Silva C, Yang J, Fonseca F, Pham H, Napimoga M, Abdalla HB, Aver G, De Oliveira M, Hammock BD, Clemente-Napimoga J. 2024. Eicosanoid profiles in an arthritis model: Effects of a soluble epoxide hydrolase inhibitor. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1869(2):159432. doi:10.1016/j.bbalip.2023.159432 PMID:37984607 PMCID:10842726
• Wang Y, Zhou H, Fu Y, Wang Z, Gao Q, Yang D, Kang J, Chen L, An Z, Hammock BD, Zhang J, Huo J. 2024. Establishment of an indirect competitive immunoassay for the detection of dicamba based on a highly specific nanobody. Sci Total Environ 917:170567. doi:10.1016/j.scitotenv.2024.170567 PMID:38296098
• Warner J, Hardesty JE, Song Y, Floyd A, Deng Z, Jebet A, He L, Zhang XH, McClain CJ, Hammock BD, Warner D, Kirpich IA. 2024. Hepatic transcriptome and its regulation following soluble epoxide hydrolase inhibition in alcohol-associated liver disease. Am J Pathol 194(1):71-84. doi:10.1016/j.ajpath.2023.09.016 PMID:37925018 PMCID:10768534

2023

• Angelia J, Weng X, Solomatov A, Chin C, Fernandez A, Hudson PK, Morisseau C, Hammock BD, Kandasamy R, Pecic S. 2023. Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behavior. Prostaglandins Other Lipid Mediat 164:106702. doi:10.1016/j.prostaglandins.2022.106702 PMID:36529320 PMCID:PMC9879382
• Atone J, Wagner KM, Koike S, Yang J, Hwang SH, Hammock BD. 2023. Inhibition of soluble epoxide hydrolase reduces paraquat neurotoxicity in rodents. Environ Toxicol Pharmacol 98:104070. doi:10.1016/j.etap.2023.104070 PMID:36682504 PMCID:PMC9992278
• Basting RT, Napimoga M, Trindade da Silva CA, Abdalla HB, Durso BC, Martins LH, Cavalcanti Hd, Hammock BD, Clemente-Napimoga JT. 2023. Soluble epoxide hydrolase inhibitor blockage microglial cell activation in subnucleus caudalis in a persistent model of arthritis. Int Immunopharmacol 120:110320. doi:10.1016/j.intimp.2023.110320 PMID:37230034
• Chen Y, Chen L, Xu H, Cao R, Morisseau C, Zhang M, Shi Y, Hammock BD, Wang J, Zhuang J, Liu Z, Chen G. 2023. Structure-directed discovery of potent soluble epoxide hydrolase inhibitors for the treatment of inflammatory disease. J Med Chem 66(4):2979-3009. doi:10.1021/acs.jmedchem.2c01996 PMID:36689364 PMCID:PMC9974930
• Deans J, Deol P, Titova N, Radi S, Vuong L, Evans J, Pan S, Fahrmann J, Yang J, Hammock BD, Fiehn O, Fekry B, Eckel-Mahan K, Sladek FM. 2023. HNF4α isoforms regulate the circadian balance between carbohydrate and lipid metabolism in the liver. Front. Endocrinol 14:1266527. doi:10.3389/fendo.2023.1266527 PMID:38111711 PMCID:10726135
• Dover M, Moseley T, Biskaduros A, Paulchakrabarti M, Hwang SH, Hammock BD, Choudhury B, Kaczor-Urbanowicz KE, Urbanowicz A, Morselli M, Dang J, Pellegrini M, Paul K, Bentolila LA, Fiala M. 2023. Polyunsaturated fatty acids mend macrophage transcriptome, glycome, and phenotype in the patients with neurodegenerative diseases, including Alzheimer's disease. Journal of Alzheimers Disease 91(1):245-261. doi:10.3233/JAD-220764 PMID:36373322 PMCID:PMC9881025
• El-Sheikh EA, Li D, Hamed I, Ashour M, Hammock BD. 2023. Residue analysis and risk exposure assessment of multiple pesticides in tomato and strawberry ad their products from markets. Foods 12(10):1936. doi:10.3390/foods12101936 PMID:37238754 PMCID:PMC1021775
• Gao Q, Huo J, Chen L, Yang D, Zhang W, Jia B, Xu X, Barnych B, Zhang J, Hammock BD. 2023. Development of immunoassay based on a specific antibody for sensitive detection of nicosulfuron in environment. Sci Total Environ 859(Pt1):160247. doi:10.1016/j.scitotenv.2022.160247 PMID:36400293 PMCID:PMC10042444
• He Q, McCoy MR, Qi M, Morisseau C, Yang H, Xu C, Shey R, Goodman MC, Zhao S, Hammock BD. 2023. The generation of a nanobody-based ELISA for human microsomal epoxide hydrolase. Int J Mol Sci 24(19):14698. doi:10.3390/ijms241914698 PMID:37834144 PMCID:PMC10572367
• He Q, McCoy MR, Yang H, Lin M, Cui X, Zhao S, Morisseau C, Li D, Hammock BD. 2023. Mix-and-read nanobody-based sandwich homogeneous split-luciferase assay for the rapid detection of human soluble epoxide hydrolase. Anal Chem 95(14):6038-6045. doi:10.1021/acs.analchem.3c00079 PMID:36972550 PMCID:PMC10335774
• Kulkarni R, Mehta R, Goswami SK, Hammock BD, Morisseau C, Hwang SH, Mallappa O, Azeemuddin MM, Rafiq M, N MS. 2023. Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygenase (COX) against chemotherapy-induced cognitive impairment in mice. Biochem Biophys Res Commun 667:64-72. doi:10.1016/j.bbrc.2023.05.008 PMID:37209564
• Lei X, Abd El-Aty AM, Xu L, Zhao J, Li J, Gao S, Zhao Y, She Y, Jin F, Wang J, Zheng L, Jin M, Hammock BD. 2023. Production of a monoclonal antibody for the detection of forchlorfenuron: application in an indirect enzyme-linked immunosorbent assay and immunochromatographic strip. Biosensors 13(2):239. doi:10.3390/bios13020239 PMID:36832005 PMCID:PMC9954037
• Leuillier M, Duflot T, Menoret S, Messaoudi H, Djerada Z, Groussard D, Denis RG, Chevalier L, Karoui A, Panthu B, Thiebaut P, Schmitz-Afonso I, Nobis S, Campart C, Henry T, Sautreuil C, Luquet SH, Beseme O, Feliu C, Peyret H, Nicol L, Henry J, Renet S, Mulder P, Wan D, Tesson L, Heslan J, Duche A, Jacques S, Ziegler F, Brunel V, Rautureau GJ, Monteil C, do Rego J, do Rego J, Afonso C, Hammock BD, Madec A, Pinet F, Richard V, Anegon I, Guignabert C, Morisseau C, Bellien J. 2023. CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury. J. Adv. Res 43:163-174. doi:10.1016/j.jare.2022.03.004 PMID:36585106 PMCID:PMC9811321
• Li J, Wu G, Li L, Wang L, Liang Y, Fang R, Zhang Q, Xie L, Shen X, Shen Y, Xu Z, Wang H, Hammock BD. 2023. Structural insights into the stability and recognition mechanism of the antiquinalphos nanobody for the detection of quinalphos in foods. Anal Chem 95(30):11306-11315. doi:10.1021/acs.analchem.3c01370 PMID:37428097
• Liu M, Chen Z, Huang X, Wang H, Zhao J, Shen Y, Luo L, Wen X, Hammock BD, Xu Z. 2023. A bispecific nanobody with high sensitivity/efficiency for simultaneous determination of carbaryl and its metabolite 1-naphthol in the soil and rice samples. Environ Pollut 335:122265. doi:10.1016/j.envpol.2023.122265 PMID:37517641
• Liu M, He X, Xu Z, Deng H, Shen Y, Luo L, Shen X, Chen Z, Hammock BD, Wang H. 2023. Development of a biotinylated nanobody-based gold nanoparticle immunochromatographic assay for the detection of procymidone in crops. J Agric Food Chem 71(35):13137-13146. doi:10.1021/acs.jafc.3c03408 PMID:37611148
• Luo A, Wu Z, Li S, McReynolds C, Wang D, Liu H, Huang C, He T, Zhang X, Wang Y, Liu C, Hammock BD, Hashimoto K, Yang CZ. 2023. The soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via the AHR and TSPO signaling. J Transl Med 21(1):71. doi:10.1186/s12967-023-03917-x PMID:36732752 PMCID:PMC9896784
• McReynolds C, Hammock BD, Morisseau C. 2023. Regulatory lipid vicinal diols counteract the biological activity of epoxy fatty acids and can act as biomarkers and mechanisms for disease progression. Pharmacol Ther 248:108454. doi:10.1016/j.pharmthera.2023.108454 PMID:37268114
• Oh YT, Yang J, Morriseau C, He Q, Hammock BD, Youn JH. 2023. Effects of individual circulating FFAs on plasma and hepatic FFA epoxides, diols, and epoxide-diol ratios as indices of soluble epoxide hydrolase activity. Int J Mol Sci 24(13):10760. doi:10.3390/ijms241310760 PMID:37445935 PMCID:PMC10341844
• Oh YT, Yang J, Stefanovski D, Hammock BD, Youn JH. 2023. Determinants of meal-induce changes in circulating FFA epoxides, diols, and diol-to-epoxide ratios as indices of soluble epoxide hydrolase activity. Int J Mol Sci 24(24):17351. doi:10.3390/ijms242417351 PMID:38139180 PMCID:PMC10743433
• Pan S, Karey E, Nieves-Cintron M, Chen Y, Hwang SH, Hammock BD, Pinkerton KE, Chen C. 2023. Effects of chronic secondhand smoke exposure on cardiovascular regulation and the role of soluble epoxide hydrolase in mice. Front Physiol 14:1185744. doi:10.3389/fphys.2023.1185744 PMID:37362438 PMCID:PMC10285070
• Peyman M, Barroso E, Turcu AL, Estrany F, Smith D, Jurado-Aguilar J, Rada P, Morisseau C, Hammock BD, Valverde AM, Palomer X, Galdeano C, Vazquez S, Vazquez-Carrera M. 2023. Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress. Biomed Pharmacother 168:115667. doi:10.1016/j.biopha.2023.115667 PMID:37826940
• Ravindran R, Kang H, McReynolds C, Sanghar GK, Chang W, Ramasamy S, Kolloli A, Kumar R, Subbian S, Hammock BD, Hartigan-O'Connor DJ, Ikram A, Haczku A, Khan IH. 2023. Dynamics of temporal immune responses in nonhuman primates and humans immunized with COVID-19 vaccines. PLoS One 18(10):e0287377. doi:10.1371/journal.pone.0287377 PMID:37856429 PMCID:PMC10586671
• Richter FC, Friedrich M, Kampschulte N, Piletic K, Alsaleh G, Zummach R, Hecker J, Pohin M, Ilott N, Guschina I, Wideman SK, Johnson E, Borsa M, Hahn P, Morriseau C, Hammock BD, Schipper HS, Edwards CM, Zechner R, Siegmund B, Weidinger C, Schebb N, Powrie F, Simon AK. 2023. Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10. EMBO J e112202. doi:10.15252/embj.2022112202 PMID:36795015 PMCID:PMC10015370
• Shen Q, Yang J, Zamora D, Horowitz M, Faurot KR, MacIntosh BA, Mann JD, Hammock BD, Ramsden CE, Taha AY. 2023. Associations between plasma lipid mediators and chronic daily headache outcomes in patients randomized to a low linoleic acid diet with or without added omega-3 fatty acids. Metabolites 13(6):690. doi:10.3390/metabo13060690 PMID:37367848 PMCID:PMC10304617
• Sun S, Ding Z, Gao L, Hammock BD, Huang X, Xu ZP, Wang X, Cheng Q, Mo F, Shi W, Xie S, Liu A, Li H, Yang X, Lu X. 2023. A dendritic/tumor fusion cell vaccine enhances efficacy of nanobody-based CAR-T cells against solid tumor. Thno 13(14):5099-5113. doi:10.7150/thno.84946 PMID:37771772 PMCID:PMC10526666
• Thai PN, Ren L, Xu W, Overton J, Timofeyev V, Nader CE, Haddad MJ, Yang J, Gomes AV, Hammock BD, Chiamvimonvat N, Sirish P. 2023. Chronic diclofenac exposure increases mitochondrial oxidative stress, inflammatory mediators, and cardiac dysfunction. Cardiovasc Drugs Ther 37(1):25-37. doi:10.1007/s10557-021-07253-4 PMID:34499283 PMCID:PMC8904649
• Vazquez J, Ginex T, Herrero A, Morisseau C, Hammock BD, Luque FJ. 2023. Screening and biological evaluation of soluble epoxide hydrolase inhibitors: Assessing the role of hydrophobicity in the pharmacophore-guided search of novel hits. J Chem Inf Model 63(10):3209-3225. doi:10.1021/acs.jcim.3c00301 PMID:37141492 PMCID:PMC10207366
• Wang W, Wagner KM, Wagner YM, Singh N, Yang J, He Q, Morisseau C, Hammock BD. 2023. Soluble epoxide hydrolase contributes to cell senescence and ER stress in aging mice colon. Int J Mol Sci 24(5):4570. doi:10.3390/ijms24054570 PMID:36901999 PMCID:PMC1000356
• Wang W, Wang Y, Wagner KM, Lee RD, Hwang SH, Morisseau C, Wulff H, Hammock BD. 2023. Aflatoxin B1 increases soluble epoxied hydrolase in the brain and induces neuroinflammation and dopaminergic neurotoxicity. Int J Mol Sci 24(12):9938. doi:10.3390/ijms24129938 PMID:37373086 PMCID:PMC10298596
• Wang W, Wang Y, Yang J, Wagner KM, Hwang SH, Cheng J, Singh N, Edwards PC, Morisseau C, Zhang G, Panigrahy D, Hammock BD. 2023. Aflatoxin B1 exposure disrupts the intestinal immune function via a soluble epoxide hydrolase-mediated manner. Ecotoxicol Environ Saf 249:114417. doi:10.1016/j.ecoenv.2022.114417 PMID:36525946 PMCID:PMC9879385
• Wang Y, Abd El-Aty AM, Wang S, Cui X, Zhao J, Lei X, Xu L, She Y, Jin F, Eun J, Shim J, Wang J, Jin M, Hammock BD. 2023. Competitive fluorescent immunosensor based on catalytic hairpin self-assembly for multiresidue detection of organophosphate pesticides in agricultural products. Food Chem 413:135607. doi:10.1016/j.foodchem.2023.135607 PMID:36773354 PMCID:PMC10013200
• Wang Y, Liu P, Ye Y, Hammock BD, Zhang C. 2023. An integrated approach to improve the assay performance of quantum dot-based lateral flow immunoassays by using silver deposition. Microchemical Journal 192:108932. doi:10.1016/j.microc.2023.108932
• Wang Y, Morisseau C, Takamura A, Wan D, Li D, Sidoli S, Yang J, Wolan DW, Hammock BD, Kitamura S. 2023. PROTAC-mediated selective degradation of cytosolic soluble epoxide hydrolase enhances ER stress reduction. ACS Chem Biol doi:10.1021/acschembio.3c00017 PMID:36947831
• Wu S, Tian J, Xue X, Ma F, Morisseau C, Hammock BD, Xu T. 2023. Biosynthesis of magnetosome-nanobody complex in Magnetospirillum gryphiswaldense MSR-1 and a magnetosome-nanobody-based enzyme-linked immunosorbent assay for the detection of tetrabromobisphenol A in water. Anal Bioanal Chem doi:10.1007/s00216-023-05005-x PMID:37934249
• Xu L, Abd El-Aty AM, Cao Z, Lei X, Zhao J, Li J, Gao S, Zhao Y, She Y, Jin F, Wang J, Jin M, Hammock BD. 2023. Generating monoclonal antibodies against buprofezin and developing immunoassays for its residue detection in tea samples. J Agric Food Chem 71(41):14967-14978. doi:10.1021/acs.jafc.3c03263 PMID:37803933
• Yang H, Qi M, He Q, Hwang SH, Yang J, McCoy MR, Morisseau C, Zhao S, Hammock BD. 2023. Quantification of soluble epoxide hydrolase inhibitors in experimental and clinical samples using the nanobody-based ELISA. J Pharm Anal 13(9):1013-1023. doi:10.1016/j.jpha.2023.05.006 PMID:37842656 PMCID:10568103
• Yang H, Vasylieva N, Wang J, Li Z, Duan W, Chen S, Wen K, Meng H, Yu X, Shen J, Hammock BD, Wang Z. 2023. Precise isolation and structural origin of an ultra-specific nanobody against chemical compound. J Hazard Mater 458:131958. doi:10.1016/j.jhazmat.2023.131958 PMID:37429192
• Yang JC, Xu P, Ning S, Wasielewski LJ, Adomat H, Hwang SH, Morisseau C, Gleave M, Corey E, Gao AC, Lara Jr PN, Evans CP, Hammock BD, Liu C. 2023. Novel inhibition of AKR1C3 and androgen receptor axis by PTUPB synergizes enzalutamide treatment in advanced prostate cancer. Oncogene doi:10.1038/s41388-022-02566-6 PMID:36596844 PMCID:PMC9975039
• Yin Z, He Q, Yang H, Morisseau C, El-Sheikh EA, Li D, Hammock BD. 2023. Development of a sandwich ELISA for the specific quantitation of hemagglutinin (HA)-tagged proteins during their inducible expression in Escherichia coli. Anal Bioanal Chem doi:10.1007/s00216-023-04846-w PMID:37505234
• Zhang J, Luan Z, Huo X, Zhang M, Morisseau C, Sun C, Hammock BD, Ma X. 2023. Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury. Int J Biol Sci 19(1):294-310. doi:10.7150/ijbs.78097 PMID:36594097 PMCID:PMC9760444
• Zhang J, Zhang M, Huo X, Ning J, Yu Z, Morisseau C, Sun C, Hammock BD, Ma X. 2023. Macrophage inactivation by small molecule wedelolactone via targeting sEH for the treatment of LPS-induced acute lung injury. ACS Cent Sci 9(3):440-456. doi:10.1021/acscentsci.2c01424
• Zhang J, Zhang W, Morisseau C, Zhang M, Dong H, Zhu Q, Huo X, Sun C, Hammock BD, Ma X. 2023. Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate matter 2.5 exposure mediated lung injury. J Hazard Mater 458:131890. doi:10.1016/j.jhazmat.2023.131890 PMID:37406527

2022

• Abdalla HB, Alvarez C, Wu Y, Rojas P, Hammock BD, Maddipati KR, Trindade-da-Sillva CA, Soares MQ, Clemente-Napimoga JT, Kantarci A, Napimoga M, Van Dyke TE. 2022. Soluble epoxide hydrolase inhibition enhances production of specialized pro-resolving lipid mediator and promotes macrophage plasticity. Br J Pharmacol 16009. doi:10.1111/bph.16009 PMID:36508312
• Abdalla HB, Napimoga M, Teixeira JM, Trindade da Silva CA, Pieroni VL, Araujo FS, Hammock BD, Clemente-Napimoga JT. 2022. Soluble epoxide hydrolase inhibition avoid formalin-induced inflammatory hyperalgesia in the temporomandibular joint. Inflammopharmacology doi:10.1007/s10787-022-00965-5 PMID:35303234
• Bergmann CB, McReynolds C, Wan D, Singh N, Goetzman H, Caldwell CC, Supp DM, Hammock BD. 2022. sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury. Proc Natl Acad Sci U S A 119:doi:10.1073/pnas.2120691119 PMID:35312372 PMCID:PMC9060469
• Chen Z, Wu H, Shen Y, Wang H, Zhang Y, Hammock BD, Li Z, Luo L, Lei H, Xu Z. 2022. Phosphate-triggered ratiometric fluoroimmunoassay based on nanobody-alkaline phosphatase fusion for sensitive detection of 1-naphthol for the exposure assessment of pesticide carbaryl. J Hazard Mater 424:doi:10.1016/j.jhazmat.2021.127411 PMID:34629198
• Chen Z, Zhang Y, Chen J, Lin Z, Wu M, Shen Y, Luo L, Wang H, Wen X, Hammock BD, Lei H, Xu Z. 2022. Production and characterization of biotinylated anti-fenitrothion nanobodies and development of sensitive fluoroimmunoassay. J Agric Food Chem 4102-4111. doi:10.1021/acs.jafc.2c00826 PMID:35333506
• Codony S, Entrena JM, Calvo-Tusell C, Jora B, Gonzalez-Cano R, Osuna S, Corpas R, Morisseau C, Perez B, Barniol-Xicota M, Grinan-Ferre C, Perez C, Rodriguez-Franco M, Martinez AL, Loza MI, Pallas M, Verhelst SH, Sanfeliu C, Feixas F, Hammock BD, Brea J, Cobos EJ, Vasquez S. 2022. Synthesis, in vitro profiling, and in vivo evaluation of benzohomoadamantane-based ureas for visceral pain: a new indication for soluble epoxide hydrolase inhibitors. J Med Chem 65(20):13660-13680. doi:10.1021/acs.jmedchem.2c00515 PMID:36222708 PMCID:PMC9620236
• Codony S, Pont C, Grinan-Ferre C, Pede-Mattatelli AD, Calvo-Tusell C, Feixas F, Osuna S, Jarne-Ferrer J, Naldi M, Bartolini M, Loza MI, Brea J, Perez B, Bartra C, Sanfeliu C, Juarez-Jimenez J, Morisseau C, Hammock BD, Pallas M, Vasquez S, Munoz-Torrero D. 2022. Discovery and in vivo proof of concept of a highly potent dual inhibitor of soluble epoxide hydrolase and acetylcholinesterase for the treatment of Alzheimers disease. J Med Chem 65(6):4909-4925. doi:10.1021/acs.jmedchem.1c02150 PMID:35271276 PMCID:PMC8958510
• Ding Y, Cui P, Chen H, Li J, Huang L, Gonzalez-Sapienza GG, Hammock BD, Wang M, Hua X. 2022. Ready-to-use immunosensor for the detection of small molecules with fast readout. Biosens Bioelectron 209:doi:10.1016/j.bios.2022.113968 PMID:35007993
• Du F, Cao R, Chen L, Sun J, Shi Y, Fu Y, Hammock BD, Zheng Z, Liu Z, Chen G. 2022. Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment of neuropathic pain. Acta Pharm Sin B 12:1377-1389. doi:10.1016/j.apsb.2021.09.018 PMID:35530144 PMCID:PMC9072249
• Escolano C, Bagan A, Turcu AL, Morisseau C, Loza MI, Brea J, Bartra C, Sanfeliu C, Hammock BD, Vazquez S. 2022. A new family of subnanomolar inhibitors of soluble epoxide hydrolase. FASEB J 36(S1):doi:10.1096/fasebj.2022.36.S1.R2281
• Gowler PR, Turnbull J, Shahtaheri M, Gohir S, Kelly T, McReynolds C, Yang J, Jha RR, Fernandes GS, Zhang W, Doherty M, Walsh DA, Hammock BD, Valdes AM, Barrett DA, Chapman V. 2022. Clinical and preclinical evidence for roles of soluble epoxide hydrolase in osteoarthritis knee pain. Arthritis Rheumatol 74(4):doi:10.1002/art.42000 PMID:34672113 PMCID:PMC8957539
• He Q, Yang L, Lin M, Yang H, Cui X, McCoy MR, Hammock BD, Fang Y, Zhao S. 2022. Generation of bioluminescent enzyme immunoassay for ferritin by single-chain variable fragment and its NanoLuc luciferase fusion. Anal Bioanal Chem doi:10.1007/s00216-022-04261-7 PMID:35945290
• Mao X, Wang Y, Jiang L, Zhang H, Zhao Y, Liu P, Liu J, Hammock BD, Zhang C. 2022. A polydopamine-coated gold nanoparticles quenching quantum dots-based dual-readout lateral flow immunoassay for sensitive detection of carbendazim in agriproducts. Biosensors 12(2):doi:10.3390/bios12020083 PMID:35200343 PMCID:PMC8869244
• Matsumoto N, Singh N, Lee KS, Barnych B, Morisseau C, Hammock BD. 2022. The epoxy fatty acid pathway enhances cAMP in mammalian cells through multiple mechanisms. Prostaglandins Other Lipid Mediat 162:doi:10.1016/j.prostaglandins.2022.106662 PMID:35779854
• Montecillo-Aguado M, Tirado-Rodriguez B, Antonio-Andres G, Morales-Martinez M, Tong Z, Yang J, Hammock BD, Hernandez-Pando R, Huerta-Yepez S. 2022. Omega-6 polyunsaturated fatty acids enhance tumor aggressiveness in experimental lung cancer model: Important role of oxylipins. Int J Mol Sci doi:10.3390/ijms23116179 PMID:35682855 PMCID:PMC9181584
• Naeem Z, Zukunft S, Gunther S, Liebner S, Weigert A, Hammock BD, Fromel T, Fleming I. 2022. Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth. Pflugers Arch doi:10.1007/s00424-022-02709-4 PMID:35648219
• Nguyen N, Morisseau C, Li D, Yang J, Lam E, Woodside DB, Hammock BD, Shih P. 2022. Soluble epoxide hydrolase is associated with postprandial anxiety decrease in healthy adult women. Int J Mol Sci 23(19):11798. doi:10.3390/ijms231911798 PMID:36233100 PMCID:PMC9569757
• Pang Q, Chen Y, Mukhtar H, Xiong J, Wang X, Xu T, Hammock BD, Wang J. 2022. Camelization of a murine single-domain antibody against aflatoxin B1 and its antigen-binding analysis. Mycotoxin Res 38:51-60. doi:10.1007/s12550-021-00433-z PMID:35023020 PMCID:PMC8754551
• Salvador J, Vasylieva N, Gonzalez-Garcia I, Jin M, Caster RW, Siegel JB, Hammock BD. 2022. Nanobody-based lateral flow immunoassay for the rapid detection of aflatoxin B1 in almond milk. ACS Food Sci Technol 2(8):1276-1282. doi:10.1021/acsfoodscitech.2c00118
• Singh N, Li D, McReynolds C, Morisseau C, Hammock BD. 2022. Improved ELISA for linoleate-derived diols in human plasma utilizing a polyHRP-based secondary tracer. Analytical Methods doi:10.1039/d2ay00272h PMID:35481804 PMCID:PMC9116231
• Song J, He K, Xing B, Pei Y, Wang D, Wang Y, Li S, Li J, Huan W, Zhang Y, Hammock BD. 2022. Rapid measurement of residual kanamycin using highly specific biomimetic recognition paper-based chip. Anal Chem 94(50):17567-17576. doi:10.1021/acs.analchem.2c03932 PMID:36458677
• Song M, Wu Q, Liu B, Li P, Jiang L, Wang Y, Dong S, Xiong Y, Hammock BD, Zhang C. 2022. Using a quantum dot bead-based lateral flow immunoassay to broadly detect the adulteration of PDE-5 inhibitors in functional foods. Analytical Methods 10:doi:10.1039/d2ay00580h PMID:35723455
• Sun C, Zhou J, Yu Z, Huo X, Zhang J, Morisseau C, Hammock BD, Ma X. 2022. Kurarinone alleviated Parkinsons disease via stabilization of epoxyeicosatrienoic acids in animal model. Proc Natl Acad Sci U S A 119:doi:10.1073/pnas.2118818119 PMID:35217618 PMCID:PMC8892522
• Wan D, Morisseau C, Hammock BD, Yang J. 2022. A fast and selective approach for profiling vicinal diols using liquid chromatography-post column derivatization-double precursor ion scanning mass spectrometry. Molecules 27(1):283. doi:10.3390/molecules27010283 PMID:35011515 PMCID:PMC8747065
• Wang F, Yang Y, Wan D, Li J, Liang Y, Li Z, Shen Y, Xu Z, Yang J, Wang H, Gettemans J, Hammock BD, Sun Y. 2022. Nanobodies for accurate recognition of iso-tenuazonic acid and development of sensitive immunoassay for contaminant detection in foods. Food Control 136:doi:10.1016/j.foodcont.2022.108835
• Wang Y, Abd El-Aty AM, Chen G, Jia H, Cui X, Xu L, Cao Z, She Y, Jin F, Zhang Y, Hacimuftuoglu A, Lamu S, Wang J, Zheng L, Jin M, Hammock BD. 2022. A competitive immunoassay for detecting triazophos based on fluorescent catalytic hairpin self-assembly. Microchimica Acta 189:doi:10.1007/s00604-022-05217-5 PMID:35190860
• Xu L, Abd El-Aty AM, Eun J, Shim J, Zhao J, Lei X, Gao S, She Y, Jin F, Wang J, Jin M, Hammock BD. 2022. Recent advances in rapid detection techniques for pesticide residue: a review. J Agric Food Chem 70(41):13093-13117. doi:10.1021/acs.jafc.2c05284 PMID:36210513
• Xu L, Abd El-Aty AM, Shim J, Eun J, Lei X, Zhao J, Zhang X, Cui X, She Y, Jin F, Zheng L, Wang J, Jin M, Hammock BD. 2022. Design and characterization of a novel hapten and preparation of monoclonal antibody for detecting atrazine. Foods 11(12):doi:10.3390/foods11121726 PMID:35741925 PMCID:PMC9223028
• Xu L, Abd El-Aty AM, Zhao J, Lei X, Zhang X, Zhao Y, Cui X, She Y, Jin F, Wang J, Jin M, Hammock BD. 2022. Obtaining a monoclonal antibody against a novel prometryn-like hapten and characterization of its selectivity for triazine herbicides. Biosensors 13(1):22. doi:10.3390/bios13010022 PMID:36671858 PMCID:PMC9855386
• Xu L, Zhang X, Abd El-Aty AM, Wang Y, Cao Z, Jia H, Salvador J, Hacimuftuoglu A, Cui X, Zhang Y, Wang K, She Y, Jin F, Zheng L, Pujia B, Wang J, Jin M, Hammock BD. 2022. A highly sensitive bio-barcode immunoassay for multi-residue detection of organophosphate pesticides based on fluorescence anti-quenching. J Pharm Anal 12(4):637-644. doi:10.1016/j.jpha.2022.05.004 PMID:36105157 PMCID:PMC9463527
• Zhang C, Li W, Li X, Wan D, Mack S, Zhang J, Wagner KM, Wang C, Tan B, Chen J, Wu C, Tsuji K, Takeuchi M, Chen Z, Hammock BD, Pinkerton KE, Yang J. 2022. Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor. PLoS One 17(4):doi:10.1371/journal.pone.0266608 PMID:35443010 PMCID:PMC9020733
• Zhou H, He C, Li Z, Huo J, Xue Y, Xu X, Qi M, Chen L, Hammock BD, Zhang J. 2022. Development of a rapid gold nanoparticle immunochromatographic strip based on the nanobody for detecting 2,4-dichlorophenoxyacetic acid. Biosensors 12(2):doi:10.3390/bios12020084 PMID:35200344 PMCID:PMC8869386

2021

• Chen G, Liu G, Jia H, Cui X, Wang Y, Li D, Zheng W, She Y, Xu D, Huang X, Abd El-Aty AM, Sun J, Liu H, Zou Y, Wang J, Jin M, Hammock BD. 2021. A sensitive bio-barcode immunoassay based on bimetallic Au@Pt nanozyme for detection of organophosphate pesticides in various agro-products. Food Chem 362:130118. doi:10.1016/j.foodchem.2021.130118 PMID:34082296
• Cui X, Abd El-Aty AM, Liu H, Jia H, Wang Y, Cao Z, Salvador J, She Y, Jin F, Wang J, Jin M, Hammock BD, Zhang C, Xu L. 2021. Enhanced bio-barcode immunoassay using droplet digital PCR for multiplex detection of organophosphate pesticides. J Agric Food Chem 69(37):PMID:34494438
• Dong J, Li Z, Wang Y, Jin M, Shen Y, Xu Z, El-Aty AA, Gee SJ, Hammock BD, Sun Y, Wang H. 2021. Generation of functional single-chain fragment variable from hybridoma and development of chemiluminescence enzyme immunoassay for determination of total malachite green in tilapia fish. Food Chem 337:127780. doi:10.1016/j.foodchem.2020.127780 PMID:32799164 PMCID:PMC7541715 (ahead of print)
• Du F, Sun W, Morisseau C, Hammock BD, Bao X, Liu Q, Wang C, Zhang T, Yang H, Zhou J, Xiao W, Zhongbo L, Chen G. 2021. Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis. Eur J Med Chem 223(14):PMID:34218083
• Fu H, Chen Z, Wang H, Luo L, Wang Y, Huang R, Xu Z, Hammock BD. 2021. Development of a sensitive non-competitive immunoassay via immunocomplex binding peptide for the determination of ethyl carbamate in wine samples. J Hazard Mater 406:124288. doi:10.1016/j.jhazmat.2020.124288 PMID:33525128
• Jankiewicz WK, Barnett SD, Stavniichuk A, Hwang SH, Hammock BD, Belayet JB, Khan AH, Imig JD. 2021. Dual sEH/COX-2 inhibition using PTUPB - a promising approach to antiangiogensis-induced nephrotoxicity. Front Pharmacol 12:doi:10.3389/fphar.2021.744776 PMID:34955823 PMCID:PMC8695932
• Martin-Lopez J, Codony S, Bartra C, Morisseau C, Loza MI, Sanfeliu C, Hammock BD, Brea J, Vazquez S. 2021. 2-(Piperidin-4-yl)acetamides as potent inhibitors of soluble epoxide hydrolase with anti-inflammatory activity. Pharmaceuticals 14(12):doi:10.3390/ph14121323 PMID:34959721 PMCID:PMC8703317
• Singh N, Vik A, Lybrand DB, Morisseau C, Hammock BD. 2021. New alkoxy- analogues of expoxyeicosatrienoic acids attenuate cisplatin nephrotoxicity in vitro via reduction of mitochondrial dysfunction, oxidative stress, mitogen-activated protein kinase signaling, and caspase activation. Chem Res Toxicol 34:2579-2591. doi:10.1021/acs.chemrestox.1c00347 PMID:34817988
• Su B, Zhang Z, Sun Z, Tang Z, Xie X, Chen Q, Cao H, Yu X, Xu Y, Liu X, Hammock BD. 2021. Fluonanobody-based nanosensor via fluorescence resonance energy transfer for ultrasensitive detection of ochratoxin A. J Hazard Mater 422:PMID:34411960
• Sun C, Zhang X, Zhou J, Huo X, Yu Z, Morisseau C, Hammock BD, Ma X. 2021. Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3 beta signaling pathway. Food Chem Toxicol 156:PMID:34411643
• Wagner KM, Yang J, Morisseau C, Hammock BD. 2021. Soluble epoxide hydrolase deletion limits high-fat diet-induced inflammation. Front Pharmacol 12:778470. doi:10.3389/fphar.2021.778470 PMID:34975481 PMCID:PMC8719166
• Wang F, Li Z, Wan D, Vasylieva N, Shen Y, Xu Z, Yang J, Gettemans J, Wang H, Hammock BD, Sun Y. 2021. Enhanced non-toxic immunodetection of Alternaria mycotoxin tenuazonic acid based on ferritin-displayed anti-idiotypic nanobody-nanoluciferase multimers. J Agric Food Chem 69:4911-4917. doi:10.1021/acs.jafc.1c01128 PMID:33870684
• Wang F, Wan D, Shen Y, Tian Y, Xiao Z, Xu Z, Yang J, Sun Y, Hammock BD, Wang H. 2021. Development of a chemiluminescence immunoassay for detection of tenuazonic acid mycotoxin in fruit juices with a specific camel polyclonal antibody dagger. Analytical Methods 8:doi:10.1039/d1ay00200g PMID:33885655
• Wang Y, Du P, Abd El-Aty AM, Chen G, Jia H, Cui X, Oz E, Zhang X, Zhang Y, Qin G, Yan F, Wang J, Jin M, Hammock BD. 2021. A visual bio-barcode immunoassay for sensitive detection of triazophos based on biochip silver staining signal amplification. Food Chem 347:129024. doi:10.1016/j.foodchem.2021.129024 PMID:33461115
• Wilt S, Kodani SD, Valencia L, Hudson PK, Sanchez S, Quintana T, Morisseau C, Hammock BD, Kandasamy R, Pecic S. 2021. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem 51:116507. doi:10.1016/j.bmc.2021.116507 PMID:34794001
• Xu B, Wang K, Vasylieva N, Zhou H, Xue X, Wang B, Li QX, Hammock BD, Xu T. 2021. Development of a nanobody-based ELISA for the detection of the insecticides cyantraniliprole and chlorantraniliprole in soil and the vegetable bok choy. Anal Bioanal Chem 413(9):2503-2511. doi:10.1007/s00216-021-03205-x PMID:33580830
• Yu S, Li Z, Li J, Zhao S, Wu S, Liu H, Bi X, Li D, Dong J, Duan S, Hammock BD. 2021. Generation of dual functional nanobody-nanoluciferase fusion and its potential in bioluminescence enzyme immunoassay for trace glypican-3 in serum. Sens Actuators B Chem 336:doi:10.1016/j.snb.2021.129717
• Zhang C, Wu X, Li D, Hu J, Wan D, Zhang Z, Hammock BD. 2021. Development of nanobody-based flow-through dot ELISA and lateral-flow immunoassay for rapid detection of 3-phenoxybenzoic acid. Analytical Methods doi:10.1039/d1ay00129a PMID:33861243
• Zhao Y, Ruan X, Song Y, Smith JN, Vasylieva N, Hammock BD, Lin Y, Du D. 2021. Smartphone-based dual-channel immunochromatographic test strip with polymer quantum dot labels for simultaneous detection of cypermethrin and 3-phenoxybenzoic acid. Anal Chem 93:PMID:34591463

2020

• El-Moghazy AY, Huo J, Amaly N, Vasylieva N, Hammock BD, Sun G. 2020. An innovative nanobody-based electrochemical immunosensor using decorated nylon nanofibers for point-of-care monitoring of human exposure to pyrethroid insecticides. ACS Appl Mater Interfaces 12:6159-6168. doi:10.1021/acsami.9b16193
• Fu H, Wang Y, Xiao Z, Wang H, Li Z, Shen Y, Lei H, Sun Y, Xu Z, Hammock BD. 2020. A rapid and simple fluorescence enzyme-linked immunosorbent assay for tetrabromobisphenol A in soil samples based on a bifunctional fusion protein. Ecotoxicol Environ Saf 188:109904. doi:10.1016/j.ecoenv.2019.109904
• He J, Ma S, Wu S, Xu J, Tian J, Li J, Gee SJ, Hammock BD, Li QX, Xu T. 2020. Construction of immunomagnetic particles with high stability in stringent conditions by site-directed immobilization of multivalent nanobodies onto bacterial magnetic particles for the environmental detection of tetrabromobisphenol-a. Anal Chem 92:1114-1121. doi:10.1021/acs.analchem.9b04177 PMID:31763820
• Hongsibsong S, Prapamontol T, Xu T, Hammock BD, Wang H, Chen Z, Xu Z. 2020. Monitoring of the organophosphate pesticide chlorpyrifos in vegetable samples from local markets in northern Thailand by developed immunoassay. Int J Environ Res Public Health 17:doi:10.3390/ijerph17134723 PMID:32630084
• Kumar S, Vasylieva N, Singh V, Hammock BD, Singh SG. 2020. A facile, sensitive and rapid sensing platform based on CoZnO for detection of fipronil; an environmental toxin. Electroanalysis 10:doi:10.1002/elan.202000051
• Li P, Yang C, Liu B, Wu Q, Wang Y, Dong S, Zhang H, Vasylieva N, Hammock BD, Zhang C. 2020. Sensitive immunochromatographic assay using highly luminescent quantum dot nanobeads as tracer for the detection of cyproheptadine hydrochloride in animal-derived food. Front Chem 8:575. doi:10.3389/fchem.2020.00575 PMID:32760698 PMCID:PMC7372008
• Qi M, Huo J, Li Z, He C, Li D, Wang Y, Vasylieva N, Zhang J, Hammock BD. 2020. On-spot quantitative analysis of dicamba in field waters using a lateral flow immunochromatographic strip with smartphone imaging. Anal Bioanal Chem doi:10.1007/s00216-020-02833-z PMID:32737550
• Spath J, Nording M, Lindberg R, Brodin T, Jansson S, Yang J, Wan D, Hammock BD, Fick J. 2020. Novel metabolomic method to assess the effect-based removal efficiency of advanced wastewater treatment techniques. Environ Chem 17:1-5. doi:10.1071/en19270
• Tang Z, Liu X, Su B, Chen Q, Cao H, Yun Y, Xu Y, Hammock BD. 2020. Ultrasensitive and rapid detection of ochratoxin A in agro-products by a nanobody-mediated FRET-based immunosensor. J Hazard Mater 387:121678. doi:10.1016/j.jhazmat.2019.121678 PMID:31753666

2019

• Chen H, Ding Y, Yang Q, Barnych B, Gonzalez-Sapienza GG, Hammock BD, Wang M, Hua X. 2019. Fluorescent turn off-on small-molecule-monitoring nanoplatform based on dendrimer-like peptides as competitors. ACS Appl Mater Interfaces 11(36):33380-33389. doi:10.1021/acsami.9b13111 PMID:31433617 PMCID:PMC7059760
• Ding Y, Hua X, Chen H, Gonazlez-Sapienza GG, Barnych B, Liu F, Wang M, Hammock BD. 2019. A dual signal immunochromatographic strip for the detection of imidaclothiz using a recombinant fluorescent-peptide tracer and gold nanoparticles. Sens Actuators B Chem 297:7. doi:10.1016/j.snb.2019.126714
• Guo W, Langenhove KV, Vandermarken T, Denison MS, Elskens M, Baeyens W, Gao Y. 2019. In situ measurement of estrogenic activity in various aquatic systems using organic diffusive gradients in thin-film coupled with ERE-CALUX bioassay. Environ Int 127:13-20. PMID:30897513
• Hongsibsong S, Prapamontol T, Dong J, Bever C, Xu Z, Gee SJ, Hammock BD. 2019. Exposure of consumers and farmers to organophosphate and synthetic pyrethroid insecticides in Northern Thailand. J Verbrauch Lebensm 14(1):17-23. doi:10.1007/s00003-019-01207-7
• Huo J, Barnych B, Li Z, Wan D, Li D, Vasylieva N, Knezevic SZ, Osipitan OA, Scott JE, Zhang J, Hammock BD. 2019. Hapten synthesis, antibody development, and a highly sensitive indirect competitive chemiluminescent enzyme immunoassay for detection of dicamba. J Agric Food Chem 67:5711-5719. doi:10.1021/acs.jafc.8b07134 PMID:31042038 PMCID:PMC6873229
• Joshi U, Pearson A, Evans JE, Langlois H, Saltiel N, Ojo J, Klimas N, Sullivan K, Keegan AP, Oberlin S, Darcey T, Cseresznye A, Raya B, Paris D, Hammock BD, Vasylieva N, Hongsibsong S, Stern LJ, Crawford F, Mullan M, Abdullah L. 2019. A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness. Brain Behav Immun 81:545-559. doi:10.1016/j.bbi.2019.07.015
• Liu Z, Wang K, Wang Z, Ding G, Hao X, Li QX, Li J, Gee SJ, Hammock BD, Xu T. 2019. Development of an immunoassay for the detection of carbaryl in cereals based on a camelid variable heavy-chain antibody domain. Journal of the Science of Food and Agriculture 99(9):4383-4390. doi:10.1002/jsfa.9672 PMID:30851058 PMCID:PMC7061733
• Luo L, Wei X, Jia B, Yang J, Shen Y, Hammock BD, Dong J, Wang H, Lei H, Xu Z. 2019. Modulating linker composition of haptens resulted in improved immunoassay for histamine. Biomolecules 9:10. doi:10.3390/biom9100597 PMID:31614550 PMCID:PMC6843301
• Mukhtar H, Ma L, Pang Q, Zhou Y, Wang X, Xu T, Hammock BD, Wang J. 2019. Cyclic peptide: a safe and effective alternative to synthetic aflatoxin B1-competitive antigens. Anal Bioanal Chem 411(17):3881-3890. doi:10.1007/s00216-019-01862-7
• Qiu Y, Li P, Liu B, Liu Y, Wang Y, Tao T, Xu J, Hammock BD, Liu X, Guan R, Zhang C. 2019. Phage-displayed nanobody based double antibody sandwich chemiluminescent immunoassay for the detection of Cry2A toxin in cereals. Food Agric Immunol 30:924-936. doi:10.1080/09540105.2019.1642307
• Riangrungroj P, Bever C, Hammock BD, Polizzi K. 2019. A label-free optical whole-cell Escherichia coli biosensor for the detection of pyrethroid insecticide exposure. Sci Rep doi:10.1038/s41598-019-48907-6 PMID:31462650 PMCID:PMC6713742
• Shu M, Xu Y, Dong J, Zhong C, Hammock BD, Wang W, Wu G. 2019. Development of a noncompetitive idiometric nanobodies phage immunoassay for the determination of fumonisin B1. Food Agric Immunol 30(1):510-21. doi:10.1080/09540105.2019.1604637
• Tang Z, Liu X, Wang Y, Chen Q, Hammock BD, Xu Y. 2019. Nanobody-based fluorescence resonance energy transfer immunoassay for noncompetitive and simultaneous detection of ochratoxin a and ochratoxin B. Environ Pollut 251:238-245. doi:10.1016/j.envpol.2019.04.135
• Wang K, Liu Z, Ding G, Li J, Vasylieva N, Li QX, Li D, Gee SJ, Hammock BD, Xu T. 2019. Development of a one-step immunoassay for triazophos using camel single-domain antibody-alkaline phosphatase fusion protein. Anal Bioanal Chem 411(6):1287-1295. doi:10.1007/s00216-018-01563-7
• Wang K, Vasylieva N, Wan D, Eads DA, Yang J, Tretten T, Barnych B, Li J, Li QX, Gee SJ, Hammock BD, Xu T. 2019. Quantitative detection of fipronil and fipronil-sulfone in sera of black-tailed prairie dogs and rats after oral exposure to fipronil by camel single-domain antibody-based immunoassays. Anal Chem 91:1532-1540. doi:10.1021/acs.analchem.8b04653
• Wang Y, Li Z, Barnych B, Huo J, Wan D, Vasylieva N, Xu J, Li P, Liu B, Zhang C, Hammock BD. 2019. Investigation of the small size of nanobodies for a sensitive fluorescence polarization immunoassay for small molecules: 3-phenoxybenzoic acid, an exposure biomarker of pyrethroid insecticides as a model. J Agric Food Chem 67(41):11536-11541. doi:10.1021/acs.jafc.9b04621
• Wang Y, Xu J, Qiu Y, Li P, Liu B, Yang L, Barnych B, Hammock BD, Zhang C. 2019. Highly specific monoclonal antibody and sensitive quantum dot beads-based fluorescence immunochromatographic test strip for tebuconazole assay in agricultural products. J Agric Food Chem 67:9096-9103. doi:10.1021/acs.jafc.9b02832 PMID:31356079 PMCID:PMC7069222

2018

• Bever C, Barnych B, Hnasko R, Cheng LW, Stanker LH. 2018. A new conjugation method used for the development of an immunoassay for the detection of amanitin, a deadly mushroom toxin. Toxins (Basel) 10(7):11. doi:10.3390/toxins10070265 PMID:29958410 PMCID:PMC6070930
• Bever C, Nording ML, Taft D, Kalanetra KM, Mills DA, Breck MA, Smilowitz JT, German JB, Hammock BD. 2018. Effects of triclosan in breast milk on the infant fecal microbiome. Chemosphere 203:467-473. doi:10.1016/j.chemosphere.2018.03.186 PMID:29635158 PMCID:PMC5915298
• Chen H, Yang Q, Ding Y, Vasylieva N, Bever C, Hua X, Wang M, Hammock BD. 2018. Competitive and noncompetitive immunoassays for the detection of benzothiostrobin using magnetic nanoparticles and fluorescein isothiocyanate-labeled peptides. Anal Bioanal Chem 1-99. doi:10.1007/s00216-018-1478-8 PMID:30478514
• Faber SC, Soshilov AA, Tagliabue SG, Bonati L, Denison MS. 2018. Comparative in vitro and in silico analysis of the selectivity of indirubin as a human Ah receptor agonist. Int J Mol Sci 19(9):2692. doi:10.3390/ijms19092692 PMID:30201897 PMCID:PMC6165432
• Haedrich J, Stumpf C, Denison MS. 2018. Ah-receptor based bioassay screening for PCDD/Fs and Dioxin-like PCBs in human milk samples from a WHO/UNEP global survey on halogenated POPs. Dtsch Lebensmitt Rundsch 114:389-397.
• Haedrich J, Stumpf C, Denison MS. 2018. Bioanalytical screening for dioxins and PCBs in EU-regulated foods: new analytical criteria adopted by the European Union in Commission Regulation (EU) 2017/644. Part 3: Assay criteria, validation and quality control, reporting of results, implementation. Dtsch Lebensmitt Rundsch 114:215-228.
• He J, Tian J, Xu J, Wang K, Li J, Gee SJ, Hammock BD, Li QX, Xu T. 2018. Strong and oriented conjugation of nanobodies onto magnetosomes for the development of a rapid immunomagnetic assay for the environmental detection of tetrabromobisphenol-A. Anal Bioanal Chem 410(25):6633-6642. doi:10.1007/s00216-018-1270-9 PMID:30066195
• Pali M, Bever C, Vasylieva N, Hammock BD, Suni II. 2018. Impedance detection of 3-phenoxybenzoic acid with a noncompetitive two-site phage anti-immunocomplex assay. Electroanalysis 30:2653-2659. doi:10.1002/elan.201800457

2017

• Cui X, Vasylieva N, Wu P, Barnych B, Yang J, Shen D, He Q, Gee SJ, Zhao S, Hammock BD. 2017. Development of an indirect competitive enzyme-linked immunosorbent assay for glycocholic acid based on chicken single-chain variable fragment antibodies. Anal Chem 89:11091-11097. doi:10.1021/acs.analchem.7b03190 PMID:28942640
• Li D, Cui Y, Morisseau C, Gee SJ, Bever C, Liu X, Wu J, Hammock BD, Ying Y. 2017. Nanobody based immunoassay for human soluble epoxide hydrolase detection using Polymeric Horseradish Peroxidase (PolyHRP) for signal enhancement: The rediscovery of PolyHRP?. Anal Chem 89(11):6248-6256. doi:10.1021/acs.analchem.7b01247 PMID:28460522 PMCID:PMC5611449
• Vasylieva N, Barnych B, Rand A, Inceoglu B, Gee SJ, Hammock BD. 2017. Sensitive immunoassay for detection and quantification of the neurotoxin, tetramethylenedisulfotetramine. Anal Chem 89(10):5612-5619. doi:10.1021/acs.analchem.7b00846 PMID:28398746
• Vasylieva N, Barnych B, Wan D, El-Sheikh EA, Nguyen HM, Wulff H, McMahen R, Strynar M, Gee SJ, Hammock BD. 2017. Hydroxy-fipronil is a new urinary biomarker of exposure to fipronil. Environ Int 103:91-98. doi:10.1016/j.envint.2017.03.012 PMID:28343720 PMCID:PMC5432128

2016

• Ahn K, Ranganathan A, Bever C, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. 2016. Detection of the antimicrobial triclosan in environmental samples by immunoassay. Environ Sci Technol 50(7):3754-3761. doi:10.1021/acs.est.5b05357 PMID:26937944 PMCID:PMC4821808
• Bever C, Dong J, Vasylieva N, Barnych B, Cui Y, Hammock BD, Gee SJ. 2016. VHH antibodies: emerging reagents for the analysis of environmental chemicals. Anal Bioanal Chem 408(22):5985-6002. doi:10.1007/s00216-016-9585-x PMID:27209591 PMCID:PMC4983233
• Gee SJ, Kennedy IR, Lee NA, Ohkawa H, Prapamontol T, Xu T. 2016. Immunoanalysis for environmental monitoring and human health. Anal Bioanal Chem 408(22):5959-5961. doi:10.1007/s00216-016-9666-x PMID:27277933

2015

• Cui Y, Li D, Morisseau C, Dong J, Yang J, Wan D, Rossotti MA, Gee SJ, Gonzalez-Sapienza GG, Hammock BD. 2015. Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase. Anal Bioanal Chem 407(24):7275-7283. doi:10.1007/s00216-015-8889-6 PMID:26229025 PMCID:PMC4573264
• Fan J, Li B, Xing S, Pan T. 2015. Reconfigurable microfluidic dilution for high-throughput quantitative assays. Lab Chip 15(12):2670-2679. doi:10.1039/c5lc00432b PMID:25994379
• Hua X, Zhou L, Feng L, Ding Y, Shi H, Wang L, Gee SJ, Hammock BD, Wang M. 2015. Competitive and noncompetitive phage immunoassays for the determination of benzothiostrobin. Anal Chim Acta 890:150-156. doi:10.1016/j.aca.2015.07.056 PMID:26347177 PMCID:PMC4791039
• Liu X, Xu Y, Wan D, Xiong Y, He Z, Wang X, Gee SJ, Ryu D, Hammock BD. 2015. Development of a nanobody-alkaline phosphatase fusion protein and its application in a highly sensitive direct competitive fluorescence enzyme immunoassay for detection of ochratoxin A in cereal. Anal Chem 87(2):1387-1394. doi:10.1021/ac504305z PMID:25531426 PMCID:PMC4476795
• Ranganathan A, Gee SJ, Hammock BD. 2015. An immunoassay for the detection of triclosan-O-glucuronide, a primary human urinary metabolite of triclosan. Anal Bioanal Chem 407(24):7263-7273. doi:10.1007/s00216-015-8918-5 PMID:26255293 PMCID:PMC4580343
• Rossotti MA, Pirez M, Gonzalez-Techera A, Cui Y, Bever C, Lee KS, Morisseau C, Leizagoyen C, Gee SJ, Hammock BD, Gonzalez-Sapienza GG. 2015. Method for sorting and pairwise selection of nanobodies for the development of highly sensitive sandwich immunoassays. Anal Chem 87(23):11907-11914. doi:10.1021/acs.analchem.5b03561 PMID:26544909 PMCID:PMC4666776
• Vasylieva N, Ahn K, Barnych B, Gee SJ, Hammock BD. 2015. Development of an immunoassay for the detection of the phenylpyrazole insecticide fipronil. Environ Sci Technol 49(16):10038-10047. doi:10.1021/acs.est.5b01005 PMID:26196357 PMCID:PMC4605820
• Wang J, Majkova Z, Bever C, Yang J, Gee SJ, Li J, Xu T, Hammock BD. 2015. One-step immunoassay for tetrabromobisphenol a using a camelid single domain antibody-alkaline phosphatase fusion protein. Anal Chem 87(9):4741-4748. doi:10.1021/ac504735p PMID:25849972 PMCID:PMC4476793

2014

• Bever C, Majkova Z, Radhakrishnan R, Suni II, McCoy MR, Wang Y, Dechant JE, Gee SJ, Hammock BD. 2014. Development and utilization of camelid VHH antibodies from alpaca for 2,2',4,4'-tetrabrominated diphenyl ether detection. Anal Chem 86(15):7875-7882. doi:10.1021/ac501807j PMID:25005746 PMCID:PMC4144723
• Chen A, Wang R, Bever C, Xing S, Hammock BD, Pan T. 2014. Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay. Biomicrofluidics 8(6):064101. doi:10.1063/1.4901348 PMID:25553178 PMCID:PMC4241779
• Dong J, Xu C, Wang H, Xiao Z, Gee SJ, Li Z, Wang F, Wu W, Shen Y, Yang J, Sun Y, Hammock BD. 2014. Enhanced sensitive immunoassay: noncompetitive phage anti-immune complex assay for the determination of malachite green and leucomalachite green. J Agric Food Chem 62(34):8752-8758. doi:10.1021/jf5019824 PMID:25077381 PMCID:PMC4150606
• Hua X, Yin W, Shi H, Li M, Wang Y, Wang H, Ye Y, Kim H, Gee SJ, Wang M, Liu F, Hammock BD. 2014. Development of phage immuno-loop-mediated isothermal amplification assays for organophosphorus pesticides in agro-products. Anal Chem 86(16):8441-8447. doi:10.1021/ac5020657 PMID:25135320 PMCID:PMC4139188
• Liu X, Xu Y, Xiong Y, Tu Z, Li Y, He Z, Qiu Y, Fu J, Gee SJ, Hammock BD. 2014. VHH phage-based competitive real-time immuno-polymerase chain reaction for ultrasensitive detection of ochratoxin A in cereal. Anal Chem 86(15):7471-7477. doi:10.1021/ac501202d PMID:24992514 PMCID:PMC4306448
• Radhakrishnan R, Suni II, Bever C, Hammock BD. 2014. Impedance biosensors: applications to sustainability and remaining technical challenges. ACS Sustain Chem Eng 2(7):1649-1655. doi:10.1021/sc500106y PMID:25068095 PMCID:PMC4105195
• Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn K, Gee SJ, Hammock BD. 2014. Determination of the pyrethroid insecticide metabolite 3-PBA in plasma and urine samples from farmer and consumer groups in northern Thailand. J Environ Sci Health B 49(1):15-22. doi:10.1080/03601234.2013.836862 PMID:24138464 PMCID:PMC4020914
• Wang J, Bever C, Majkova Z, Dechant JE, Yang J, Gee SJ, Xu T, Hammock BD. 2014. Heterologous antigen selection of camelid heavy chain single domain antibodies against tetrabromobisphenol A. Anal Chem 86(16):8296-8302. doi:10.1021/ac5017437 PMID:25068372 PMCID:PMC4139172

2013

• Han J, Kim H, Sudheendra L, Gee SJ, Hammock BD, Kennedy IM. 2013. Photonic crystal lab-on-a-chip for detecting staphylococcal entertoxin B at low attomolar concentration. Anal Chem 85(6):3104-3109. doi:10.1021/ac303016h PMID:23418954 PMCID:PMC3608201
• Han J, Kim H, Sudheendra L, Hass EA, Gee SJ, Hammock BD, Kennedy IM. 2013. Electrophoretic build-up of multi nanoparticle array for a highly sensitive immunoassay. Biosens Bioelectron 41:302-308. doi:10.1016/j.bios.2012.08.042 PMID:23021853 PMCID:PMC3525773
• Ranganathan A, Paradise GA, Hansen CA, McCoy MR, Gee SJ, Zhong P, Chang D, Hammock BD. 2013. Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. J Agric Food Chem 61(28):6964-6970. doi:10.1021/jf401302y PMID:23767873 PMCID:PMC3723731
• Trunnelle KJ, Bennett DH, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hennessy-Burt TE, Hammock BD, Schenker MB. 2013. Pyrethroids in house dust from the homes of farm worker families in the MICASA study. Environ Int 61:57-63. doi:10.1016/j.envint.2013.09.007 PMID:24096042 PMCID:PMC4059492
• Wang Y, Li P, Majkova Z, Bever C, Kim H, Zhang Q, Dechant JE, Gee SJ, Hammock BD. 2013. Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay. Anal Chem 85(17):8298-8303. doi:10.1021/ac4015885 PMID:23965250 PMCID:PMC3787825
• Wang Y, Wang H, Li P, Zhang Q, Kim H, Gee SJ, Hammock BD. 2013. Correction to: Phage- displayed peptide that mimics aflatoxins and its application in immunoassay. J Agric Food Chem 61(16):3994. doi:10.1021/jf401235p
• Wang Y, Wang H, Li P, Zhang Q, Kim H, Gee SJ, Hammock BD. 2013. Phage-displayed peptide that mimics aflatoxins and its application in immunoassay. J Agric Food Chem 61(10):2426–2433. doi:10.1021/jf4004048 PMID:23394544 PMCID:PMC3830680

2012

• Ahn K, Kasagami T, Tsai H, Schebb N, Ogunyoku TA, Gee SJ, Young TM, Hammock BD. 2012. An immunoassay to evaluate human/environmental exposure to the antimicrobial triclocarban. Environ Sci Technol 46:374-381. doi:10.1021/es202494d PMID:22077920 PMCID:PMC3258304 (Completed with ARRA Funds)
• Kim H, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD, McCoy MR. 2012. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Anal Chem 84(2):1165-1171. doi:10.1021/ac2030255 PMID:22148739 PMCID:PMC3264785
• Kim H, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD. 2012. Correction to isolation of alpaca antihapten heavy chain single domain antibodies for development of sensitive immunioassay. Anal Chem 84(15):6919–6919. doi:10.1021/ac301927h PMID:22830304 PMCID:PMC3460544
• McCoy MR, Yang Z, Fu X, Ahn K, Gee SJ, Bom DC, Zhong P, Chang D, Hammock BD. 2012. Monitoring of total type II pyrethroid pesticides in citrus oils and water by converting to a common product 3-phenoxybenzoic acid. J Agric Food Chem 60:5065-5070. doi:10.1021/jf2051653 PMID:22486225 PMCID:PMC3412423
• Schebb N, Ahn K, Dong H, Gee SJ, Hammock BD. 2012. Whole blood is the sample matrix of choice for monitoring systemic triclocarbon levels. Chemosphere 87(7):825-827. doi:10.1016/j.chemosphere.2011.12.077 PMID:22273184 PMCID:PMC3538789 (Completed with ARRA Funds)
• Schebb N, Franze B, Maul R, Ranganathan A, Hammock BD. 2012. In vitro glucuronidation of the antibacterial triclocarban and its oxidative metabolites. Drug Metab Dispos 40:25-31. doi:10.1124/dmd.111.042283 PMID:21953915 PMCID:PMC3250046 (Completed with ARRA Funds)
• Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn K, Gee SJ, Hammock BD. 2012. An enzyme-linked immunosorbent assay for detecting 3-phenoxybenzoic acid in plasma and its application to farmers and consumers. Analytical Methods 4:3772-3778. doi:10.1039/c2ay25642h PMID:23667388 PMCID:PMC3646417

2011

• Abdu E, Bruun DA, Yang DR, Yang J, Inceoglu B, Hammock BD, Alkayed NJ, Lein PJ. 2011. Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures. J Neurochem 117:632-642. doi:10.1111/j.1471-4159.2010.07139.x PMID:21155804 PMCID:PMC3081369
• Ahn K, Gee SJ, Aronov PA, Vega H, Krieger RI, Hammock BD, Kim H. 2011. Immunochemical analysis of 3-phenoxybenzoic acid, a biomarker of forestry worker exposure to pyrethroid insecticides. Anal Bioanal Chem 401(4):1285-1293. doi:10.1007/s00216-011-5184-z PMID:21717113 PMCID:PMC3848323
• Ahn K, Kim H, McCoy MR, Gee SJ, Hammock BD. 2011. Immunoassays and biosensors for monitoring environmental and human exposure to pyrethroid insecticides. J Agric Food Chem 59(7):2792-2802. doi:10.1021/jf1033569 PMID:21105656 PMCID:PMC3070843
• Gee SJ, Gonazlez-Sapienza GG, Hammock BD, Kim H, McCoy MR. 2011. Noncompetitive phage anti-immunocomplex real-time polymerase chain reaction for sensitive detection of small molecules. Anal Chem 83(1):246-253. doi:10.1021/ac102353z PMID:21141939 PMCID:PMC3031424
• Kim Y, Lee E, Kim K, Lee YT, Hammock BD, Lee H. 2011. Competitive immunochromatographic assay for the detection of the organophosphorus pesticide chlorpyrifos. Anal Chim Acta 693(1-2):106-113. doi:10.1016/j.aca.2011.03.011 PMID:21504817 PMCID:PMC3927651
• Schebb N, Huby M, Morisseau C, Hwang SH, Hammock BD. 2011. Development of an online SPE-LC-MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors. Anal Bioanal Chem 400(5):1359-1366. doi:10.1007/s00216-011-4861-2 PMID:21479549 PMCID:PMC3081056
• Schebb N, Inceoglu B, Ahn K, Morisseau C, Gee SJ, Hammock BD. 2011. Investigation of human exposure to triclocarban after showering and preliminary evaluation of its biological effects. Environ Sci Technol 45:3109-3115. doi:10.1021/es103650m PMID:21381656 PMCID:PMC3470465 (Completed with ARRA Funds)
• Tabares-da Rosa S, Rossotti MA, Carleiza C, Carrion F, Pritsch O, Ahn K, Last JA, Hammock BD, Gonzalez-Sapienza GG. 2011. Competitive selection from single domain antibody libraries allows isolation of high-affinity antihapten antibodies that are not favored in the llama immune response. Anal Chem 83:7213-7220. doi:10.1021/ac201824z PMID:21827167 PMCID:PMC3193053
• Ye X, Zhou X, Furr J, Ahn K, Hammock BD, Gray EL, Calafat AM. 2011. Biomarkers of exposure to triclocarban in urine and serum. Toxicology 286(1-30):69-74. doi:10.1016/j.tox.2011.05.008 PMID:21635932 PMCID:PMC3534749 (Completed with ARRA Funds)

2010

• Carlomagno M, Matho C, Cantou G, Sanborn JR, Last JA, Hammock BD, Roel A, Gonzalez D, Gonzalez-Sapienza GG. 2010. A clomazone immunoassay to study the environmental fate of the herbicide in rice (Oryza sativa) agriculture. J Agric Food Chem 58(7):4367-4371. doi:10.1021/jf9043259 PMID:20302341 PMCID:PMC2878771
• Garcia-Nieto E, Nichkova MJ, Yanez L, Costilla-Salazar R, Torres-Dosal A, Gee SJ, Hammock BD, Juarez-Santacruz L, Diaz-Barriga F. 2010. Assessment of dioxin-like soil contamination in Mexico by enzyme-linked immunosorbent assay. Arch Environ Contam Toxicol 58(4):918-926. doi:10.1007/s00244-009-9422-8 PMID:20091164 PMCID:PMC3033344
• Kim H, Rossotti MA, Ahn K, Gonzalez-Sapienza GG, Gee SJ, Musker R, Hammock BD. 2010. Development of a noncompetitive phage anti-immunocomplex assay for brominated diphenyl ether 47. Anal Biochem 401(1):38-46. doi:10.1016/j.ab.2010.01.040 PMID:20152791 PMCID:PMC2861364
• Rossotti MA, Carlomagno M, Gonzalez-Techera A, Hammock BD, Last JA, Gonzalez-Sapienza GG. 2010. Phage anti-immunocomplex assay for clomazone: two-site recognition increasing assay specificity and facilitating adaptation into an on-site format. Anal Chem 82(21):8838-8843. doi:10.1021/ac101476f PMID:20886819 PMCID:PMC3025275

2009

• Ahn K, Gee SJ, Tsai H, Bennett DH, Nishioka M, Blum A, Fishman E, Hammock BD. 2009. Immunoassay for monitoring environmental and human exposure to the polybrominated diphenyl ether BDE-47. Environ Sci Technol 43(20):7784-7790. doi:10.1021/es9009037 PMID:19921894 PMCID:PMC3528349
• Ai D, Pang W, Li N, Xu M, Jones PD, Yang J, Zhang Y, Chiamvimonvat N, Shyy JY, Hammock BD, Zhu Y. 2009. Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy. Proc Natl Acad Sci U S A 106(2):564-569. doi:10.1073/pnas.0811022106 PMID:19126686 PMCID:PMC2626743
• Inceoglu AB, Waite T, Christiansen JA, McAbee RD, Kamita SG, Hammock BD, Cornel AJ. 2009. A rapid luminescent assay for measuring cytochrome P450 activity in individual larval Culex pipiens complex mosquitoes (Diptera: Culicidae). Journal of Medical Entomology 46(1):83-92. doi:10.1603/033.046.0111 PMID:19198521 PMCID:PMC3522461
• Kim HJ, Ahn K, Gonzalez-Techera A, Gonzalez-Sapienza GG, Gee SJ, Hammock BD. 2009. Magnetic bead-based phage anti-immunocomplex assay (PHAIA) for the detection of the urinary biomarker 3-phenoxybenzoic acid to assess human exposure to pyrethroid insecticides. Anal Biochem 386(1):45-52. doi:10.1016/j.ab.2008.12.003 PMID:19101498 PMCID:PMC2863013
• Ma Z, Dosev D, Nichkova MJ, Dumas RK, Gee SJ, Hammock BD, Kennedy IM. 2009. Synthesis and characterization of multifunctional silica core-shell nanocomposites with magnetic and fluorescent functionalities. J Magn Magn Mater 321(10):1368-1371. doi:10.1016/j.jmmm.2009.02.040 PMID:20336173 PMCID:PMC2844650
• Ma Z, Dosev D, Nichkova MJ, Gee SJ, Hammock BD, Kennedy IM. 2009. Synthesis and bio-functionalization of multifunctional magnetic Fe3O4@Y2O3:Eu nanocomposites. J Mater Chem 19:4695-4700. doi:10.1039/B901427F PMID:20357905 PMCID:PMC2847302
• Nichkova MJ, Fu X, Yang Z, Zhong P, Sanborn JR, Chang D, Gee SJ, Hammock BD. 2009. Immunochemical screening of pesticides (simazine and cypermethrin) in orange oil. J Agric Food Chem 57(13):56735679. doi:10.1021/jf900652a PMID:19526986 PMCID:PMC3033343
• Parrish AR, Chen G, Burghardt RC, Watanabe T, Hammock BD, Morisseau C. 2009. Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase. Cell Biol Toxicol 25(3):217-225. doi:10.1007/s10565-008-9071-0 PMID:18386137 PMCID:PMC3033346
• Shen S, Zhang F, Zeng S, Tian Y, Chai X, Gee SJ, Hammock BD, Zheng J. 2009. Development of enantioselective polyclonal antibodies to detect styrene oxide protein adducts. Anal Chem 81(7):2668-2677. doi:10.1021/ac8023262 PMID:19245253 PMCID:PMC3463234

2008

• Chen J, Ahn K, Gee NA, Ahmed MI, Duleba AJ, Zhao L, Gee SJ, Hammock BD, Lasley BL. 2008. Triclocarban enhances testosterone action: a new type of endocrine disruptor?. Endocrinology 149(3):1173-1179. doi:10.1210/en.2007-1057 PMID:18048496 PMCID:PMC2275366
• Corenblum MJ, Wise VE, Georgi K, Hammock BD, Doris PA, Fornage M. 2008. Altered soluble epoxide hydrolase gene expression and function and vascular disease risk in the stroke-prone spontaneously hypertensive rat. Hypertension 51(2):567-73. PMID:18086949
• Dreisbach AW, Rice JC, Japa S, Newman JW, Sigel A, Gill R, Hess AE, Cemo AC, Fonseca JP, Hammock BD, Lertora JJ, Hamm LL. 2008. Salt loading increases urinary excretion of linoleic acid diols and triols in healthy human subjects. Hypertension 51:755-761. PMID:18227407
• Enayetallah AE, Luria A, Luo B, Tsai H, Sura P, Hammock BD, Grant DF. 2008. Opposite regulation of cholesterol levels by the phosphatase and hydrolase domains of soluble epoxide hydrolase. J Biol Chem 283(52):36592-36598. doi:10.1074/jbc.M806315200 PMID:18974052 PMCID:PMC2605982
• Fife KL, Liu Y, Schmelzer KR, Tsai H, Kim I, Morisseau C, Hammock BD, Kroetz DL. 2008. Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation. J Pharmacol Exp Ther 327(3):707-715. doi:10.1124/jpet.108.142398 PMID:18815352 PMCID:PMC2761654
• Gonzalez-Techera A, Umpierrez-Failache M, Cardozo S, Obal G, Last JA, Gee SJ, Hammock BD, Gonzalez-Sapienza GG, Pritsch O. 2008. High-throughput method for ranking the affinity of peptide ligands selected from phage display libraries. Bioconjug Chem 19(5):993-1000. doi:10.1021/bc700279y PMID:18393454 PMCID:PMC2863005
• Harris TR, Aronov PA, Hammock BD. 2008. Soluble epoxide hydrolase homologs in Strongylocentrotus purpuratus suggest a gene duplication event and subsequent divergence. DNA Cell Biol 27(9):467-477. doi:10.1089/dna.2008.0751 PMID:18554159 PMCID:PMC2858585
• Kim HJ, Gonzalez-Techera A, Gonzalez-Sapienza GG, Ahn K, Gee SJ, Hammock BD. 2008. Phage-borne peptidomimetics accelerate the development of polyclonal antibody-based heterologous immunoassays for the detection of pesticide metabolites. Environ Sci Technol 42(6):2047-53. doi:10.1021/es702219a PMID:18409635
• Park E, Duarte Tagles H, Gee SJ, Hammock BD, Lee K, Schenker MB. 2008. Recruiting strategy and 24-hour biomonitoring of paraquat in agricultural workers. J Agromedicine 13(4):207-217. doi:10.1080/10599240802454528 PMID:19064412 PMCID:PMC2864554
• Van Emon JM, Chuang J, Lordo RA, Schrock ME, Nichkova MJ, Gee SJ, Hammock BD. 2008. An enzyme-linked immunosorbent assay for the determination of dioxins in contaminated sediment and soil samples. Chemosphere 72(1):95-103. doi:10.1016/j.chemosphere.2008.01.012 PMID:18313102 PMCID:PMC2858573

2007

• Ahn K, Lohstroh PN, Gee SJ, Gee NA, Lasley BL, Hammock BD. 2007. High-throughput automated luminescent magnetic particle-based immunoassay to monitor human exposure to pyrethroid insecticides. Anal Chem 79(23):8883-8890. doi:10.1021/ac070675l PMID:17983205
• Ai D, Fu Y, Guo D, Tanaka H, Wang N, Tang C, Hammock BD, Shyy JY, Zhu Y. 2007. Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. Proc Natl Acad Sci U S A 104(21):9018-23. PMID:17495027
• Chen J, Ahn K, Gee SJ, Gee NA, Hammock BD, Lasley BL. 2007. Antiandrogenic properties of parabens and other phenolic containing small molecules in personal care products. Toxicol Appl Pharmacol 221(3):278-284. doi:10.1016/j.taap.2007.03.015 PMID:17481686 PMCID:PMC1978490
• Dosev D, Nichkova MJ, Dumas RK, Gee SJ, Hammock BD, Liu K, Kennedy IM. 2007. Magnetic/luminescent core/shell particles synthesized by spray pyrolysis and their application in immunoassays with internal standard. Nanotechnology 18(5):055102(6pp). PMID:18974844
• Gonzalez-Techera A, Kim HJ, Gee SJ, Last JA, Hammock BD. 2007. Polyclonal antibody-based noncompetitive immunoassay for small analytes developed with short peptide loops isolated from phage libraries. Anal Chem 79(23):9191-9196. doi:10.1021/ac7016713 PMID:17973501 PMCID:PMC2556293
• Gonzalez-Techera A, Vanrell L, Last JA, Hammock BD, Gonzalez-Sapienza GG. 2007. Phage anti-immune complex assay: general strategy for noncompetitive immunodetection of small molecules. Anal Chem 79(20):7799-7806. doi:10.1021/ac071323h PMID:17845007 PMCID:PMC2519879
• Hillard CJ, Ho WS, Thompson J, Gauthier KM, Wheelock CE, Huang H, Hammock BD. 2007. Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. Br J Pharmacol 152(5):691-8. PMID:17891162
• Kim H, Gee SJ, Li QX, Hammock BD. 2007. Noncompetitive Fluorescent Immunoassay for the Detection of the Human Urinary Biomarker 3-Phenoxybenzoic Acid with Bench Top Immunosensor KinExATM 3000. Chapter 11in: Rational Environmental Management of Agrochemicals: Risk Assessment, Monitoring, and Remedial Action. pp.171185.
• Kim HJ, Ahn K, Ma S, Gee SJ, Hammock BD. 2007. Development of sensitive immunoassays for the detection of the glucuronide conjugate of 3-phenoxybenzyl alcohol, a putative human urinary biomarker for pyrethroid exposure. J Agric Food Chem 55(10):3750-7. PMID:17455946
• Kim I, Nishi K, Tsai H, Bradford T, Koda Y, Watanabe T, Morisseau C, Blanchfield J, Toth I, Hammock BD. 2007. Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorg Med Chem 15(1):312-23. PMID:17046265
• Nichkova MJ, Dosev D, Davies AE, Gee SJ, Kennedy IM, Hammock BD. 2007. Multiplexed immunoassays for biomonitoring of exposure to agrochemicals using quantum dots as fluorescent reporters. Proc SPIE Int Soc Opt Eng 6448:644817-1. doi:10.1117/12.699231
• Nichkova MJ, Dosev D, Gee SJ, Hammock BD, Kennedy IM. 2007. Multiplexed immunoassays for proteins using magnetic luminescent nanoparticles for internal calibration. Anal Biochem 369(a):34-40. PMID:17681270
• Yuan W, Chung JS, Gee SJ, Hammock BD, Zheng J. 2007. Development of polyclonal antibodies for the detection of styrene oxide modified proteins. Chem Res Toxicol 20(2):316-321. doi:10.1021/tx600340c PMID:17266334 PMCID:PMC2565645

2006

• Ahn K, Ma S, Tsai H, Gee SJ, Hammock BD. 2006. An immunoassay for a urinary metabolite as a biomarker of human exposure to the pyrethroid insecticide permethrin. Anal Bioanal Chem 384(3):713-722. PMID:16416099
• Cummins CM, Koivunen ME, Stephanian A, Gee SJ, Hammock BD, Kennedy IM. 2006. Application of europium(III) chelate-dyed nanoparticle labels in a competitive atrazine fluoroimmunoassay on an ITO waveguide. Biosens Bioelectron 21(7):1077-1085. PMID:16368482
• Inceoglu B, Jinks SL, Schmelzer KR, Waite T, Kim I, Hammock BD. 2006. Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain. Life Sciences 79(24):2311-2319. PMID:16962614
• Koivunen ME, Dettmer K, Vermeulen R, Bakke B, Gee SJ, Hammock BD. 2006. Improved methods for urinary atrazine mercapturate analysis--assessment of an enzyme-linked immunosorbent assay (ELISA) and a novel liquid chromatography-mass spectrometry (LC-MS) method utilizing online solid phase extraction (SPE). Anal Chim Acta 572(2):180-189. doi:10.1016/j.aca.2006.05.037 PMID:17723476
• Lin C, Boland BC, Lee YJ, Salemi MR, Morin D, Miller LA, Plopper CG, Buckpitt AR. 2006. Identification of proteins adducted by reactive metabolites of naphthalene and 1-nitronaphthalene in dissected airways of rhesus macaques. Proteomics 6(3):972-982. PMID:16453347
• Morisseau C, Newman JW, Tsai H, Baecker PA, Hammock BD. 2006. Peptidyl-urea based inhibitors of soluble epoxide hydrolases. Bioorg Med Chem Lett 16(20):5439-5444. doi:10.1016/j.bmcl.2006.07.073 PMID:16908134 PMCID:PMC1892215
• Nording M, Nichkova MJ, Spinnel E, Persson Y, Gee SJ, Hammock BD, Haglund P. 2006. Rapid screening of dioxin-contaminated soil by accelerated solvent extraction/purification followed by immunochemical detection. Anal Bioanal Chem 385(2):357-366. PMID:16598456
• Wheelock AM, Morin D, Bartosiewicz MJ, Buckpitt AR. 2006. Use of a fluorescent internal protein standard to achieve quantitative two-dimensional gel electrophoresis. Proteomics 6(5):1385-1398. PMID:16429456

2005

• Ahn K, Gee SJ, Kim HJ, Nichkova MJ, Hammock BD. 2005. Progress in the development of biosensors for environmental and human monitoring of agrochemicals. Proceedings of the American Chemical Society Pacifichem 966:138-154.
• Dosev D, Nichkova MJ, Liu M, Guo B, Liu G, Hammock BD, Kennedy IM. 2005. Application of luminescent Eu:Gd2O3 nanoparticles to the visualization of protein micropatterns. J Biomed Opt 10(6):064006. doi:10.1117/1.2136347 PMID:16409071
• Dosev D, Nichkova MJ, Liu M, Guo B, Liu G, Xia Y, Hammock BD, Kennedy IM. 2005. Application of fluorescent Eu:Gd2O3 nanoparticles to the visualization of protein micropatterns. Chapter 5699 in: Imaging, Manipulation, and Analysis of Biomolecules and Cells: Fundamentals and Applications: III (Proceedings of SPIE). SPIE Society of Photo-Optical Instrumentation Engineering, San Jose, CA. pp.473-481.
• Hennebold JD, Mah K, Perez W, Vance JE, Stouffer RL, Morisseau C, Hammock BD, Adashi EY. 2005. Identification and characterization of an ovary-selective isoform of epoxide hydrolase. Biol Reprod 72(4):968-975. doi:10.1095/biolreprod.104.035899 PMID:15601917
• Huang H, Fleming CD, Nishi K, Redinbo MR, Hammock BD. 2005. Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases. Chem Res Toxicol 18(9):1371-1377. PMID:16167828
• Huang H, Stok JE, Stoutamire DW, Gee SJ, Hammock BD. 2005. Development of optically pure pyrethroid-like fluorescent substrates for carboxylesterases. Chem Res Toxicol 18(3):516-527. doi:10.1021/tx049773h PMID:15777092
• Isbell MA, Morin D, Boland BC, Buckpitt AR, Salemi MR, Presley JM. 2005. Identification of proteins adducted by reactive naphthalene metabolites in vitro. Proteomics 5(16):4197-4204. PMID:16206326
• Koivunen ME, Gee SJ, Park E, Lee K, Schenker MB, Hammock BD. 2005. Application of an enzyme-linked immunosorbent assay for the analysis of paraquat in human-exposure samples. Arch Environ Contam Toxicol 48(2):184-190. doi:10.1007/s00244-003-0251-x PMID:15696345
• Lin C, Isbell MA, Morin D, Boland BC, Salemi MR, Jewell WT, Weir AJ, Fanucchi MV, Baker GL, Plopper CG, Buckpitt AR. 2005. Characterization of a structurally intact in situ lung model and comparison of naphthalene protein adducts generated in this model vs. lung rway incubation in situ vs. lung microsomes. Chem Res Toxicol 18(5):802-813.
• Mak SK, Shan G, Lee H, Watanabe T, Stoutamire DW, Gee SJ, Hammock BD. 2005. Development of a class selective immunoassay for the type II pyrethroid insecticides. Anal Chim Acta 534:109-120.
• Nichkova MJ, Dosev D, Gee SJ, Hammock BD, Kennedy IM. 2005. Microarray immunoassay for phenoxybenzoic acid using polymer encapsulated Eu:Gd2O3 nanoparticles as fluorescent labels. Anal Chem 77(21):6864-6873. doi:10.1021/ac050826p PMID:16255584
• Phimister AJ, Nagasawa HT, Buckpitt AR, Plopper CG. 2005. Prevention of naphthalene-induced pulmonary toxicity by glutathione prodrugs: roles for glutathione depletion in adduct formation and cell injury. J Biochem Mol Toxicol 19(1):42-51. PMID:15736154
• Wheelock AM, Boland BC, Isbell MA, Morin D, Wegesser TC, Plopper CG, Buckpitt AR. 2005. In Vivo effects of ozone exposure on protein adduct formation by 1-nitronaphthalene rat lung. Am J Respir Crit Care Med 33(2):130-137. PMID:15845863
• Wheelock CE, Miller JL, Miller MJ, Phillips BM, Gee SJ, Tjeerdema RS, Hammock BD. 2005. Influence of container adsorption upon observed pyrethroid toxicity to Ceriodaphnia dubia and Hyalella azteca. Aquat Toxicol 74(1):47-52. PMID:15951033

2004

• Ahn K, Watanabe T, Gee SJ, Hammock BD. 2004. Hapten and antibody production for a sensitive immunoassay determinining a human urinary metabolite of the pyrethroid insecticide permethrin. J Agric Food Chem 52(15):4583-4594. PMID:15264887
• Boland BC, Lin C, Morin D, Miller LA, Plopper CG, Buckpitt AR. 2004. Site specific metabolism of naphthalene and 1-nitronaphthalene in dissected airways of Rhesus macaques. J Pharmacol Exp Ther 310(2):546-554. PMID:15082753
• Kennedy IM, Koivunen ME, Gee SJ, Cummins CM, Perron R, Dosev D, Hammock BD. 2004. Nanoscale fluoro-immuno assays with lanthanide oxide nanoparticles. Chapter 5593 in: Nanosensing: Materials and Devices (Proceedings of SPIE). SPIE Society of Photo-Optical Instrumentation Engineering, Bellingham, WA. pp.329-339.
• Lee H, Shan G, Ahn K, Park E, Watanabe T, Gee SJ, Hammock BD. 2004. Development of an enzyme-linked Immunosorbent assay for the pyrethroid cypermethrin. J Agric Food Chem 52(2):1039-1043. PMID:14995094
• Nichkova MJ, Park E, Koivunen ME, Kamita SG, Gee SJ, Chuang J, Van Emon JM, Hammock BD. 2004. Immunochemical determination of dioxins in environmental and biological samples. Talanta 63:1213-1223. PMID:18969550
• Park E, Kim J, Gee SJ, Watanabe T, Ahn K, Hammock BD. 2004. Determination of pyrethroid residues in agricultural products by an enzyme-linked immunosorbent assay. J Agric Food Chem 52(18):5572-5576. PMID:15373394
• Phimister AJ, Lee MG, Morin D, Buckpitt AR, Plopper CG. 2004. Glutathione depletion is a major determinant of inhaled naphthalene respiratory toxicity and naphthalene metabolism in mice. Toxicol Sci 82(1):268-278. PMID:15319489
• Rufo C, Hammock BD, Gee SJ, Last JA, Gonzalez-Sapienza GG. 2004. Robust and sensitive monoclonal enzyme-linked immunosorbent assay for the herbicide molinate. J Agric Food Chem 52(2):182-187. PMID:14733492
• Shan G, Huang H, Stoutamire DW, Gee SJ, Leng G, Hammock BD. 2004. A sensitive class specific immunoassay for the detection of pyrethroid metabolites in human urine. Chem Res Toxicol 17(2):218-225. PMID:14967009

2003

• Cho YA, Kim Y, Hammock BD, Lee YT, Lee H. 2003. Development of a microtiter plate ELISA and a dipstick ELISA for the determination of the organophosphorus insecticide fenthion. J Agric Food Chem 51(27):7854-7860. PMID:14690364
• Feng J, Mack JS, Shan G, Hammock BD. 2003. C60 nanoparticle quenching used as a biological label. In: Proceedings of SPIE (The International Society for Optical Engineering). pp.156-163.
• Feng J, Shan G, Hammock BD, Kennedy IM. 2003. Fluorescence quenching competitive immunoassay in micro droplets. Biosens Bioelectron 18(8):1055-1063. PMID:12782469
• Feng J, Shan G, Maquieira A, Koivunen ME, Guo B, Hammock BD. 2003. Functionalized europium oxide nanoparticles used as a fluorescent label in an immunoassay for atrazine. Anal Chem 75(19):5282-5286.
• Kim Y, Cho YA, Lee H, Lee YT, Gee SJ, Hammock BD. 2003. Synthesis of haptens for immunoassay of organophosphorus pesticides and effect of heterology in hapten spacer arm length of immunoassay sensitivity. Anal Chim Acta 475(1-2):85-96.
• Lee H, Watanabe T, Gee SJ, Hammock BD. 2003. Application of an enzyme-linked immunosorbent assay (ELISA) to determine deltamethrin residues in milk. Bull Environ Contam Toxicol 71(1):14-20. PMID:12945836
• Lee JK, Ahn K, Stoutamire DW, Gee SJ, Hammock BD. 2003. Development of an enzyme-linked immunosorbent assay for the detection of the organophosphorus insecticide acephate. J Agric Food Chem 51(13):3695-3703. PMID:12797729
• Nichkova MJ, Feng J, Sanchez-Baeza F, Marco M, Hammock BD, Kennedy IM. 2003. Competitive quenching fluorescence immunoassy for chlorophenols based on laser-induced fluorescence detection in microdroplets. Anal Chem 75(1):83-90. PMID:12530822
• Szekacs A, Le HM, Szurdoki F, Hammock BD. 2003. Optimization and validation of an enzyme immunoassay for the insect growth regulator fenoxycarb. Anal Chim Acta 487(1):15-29.

2002

• Cho YA, Lee H, Park EY, Lee YT, Hammock BD, Ahn K, Lee JK. 2002. Development of an ELISA for the organophosphorus insecticide chlorpyrifos. Bulletin of the Korean Chemical Society 23(3):481-487.
• Dedos SG, Szurdoki F, Szekacs A, Shiotsuki T, Hammock BD, Shimada J, Fugo H. 2002. Fenoxycarb levels and their effects on general and juvenile hormone esterase activity in the hemolymph of the silkworm, Bombyx mori. Pesticide Biochemistry and Physiology 73(3):174-187.
• Denison MS, Nagy SR, Ziccardi MH, Clark GC, Chu MD, Brown DJ, Shan G, Sugawara Y, Gee SJ, Sanborn JR, Hammock BD. 2002. Bioanalytical approaches for the detection of dioxin and related halogenated aromatic hydrocarbons. In: Biomarkers of Environmentally Associated Disease: Technologies, Concepts, and Perspectives. CRC Press Company, Boca Raton, FL. pp.483-494.
• Feng J, Shan G, Hammock BD, Kennedy IM. 2002. Fluorescence quenching competitive fluoroimmunoassay in micro droplets. In: Methods for Ultrasensitive Detection II, Proceedings of the International Society for Optical Engineering. SPIE, Bellingham, WA. pp.118-127.
• Harcourt RL, Horne I, Sutherland TD, Hammock BD, Russell RJ, Oakeshott JG. 2002. Development of a simple and sensitive fluorimetric method for isolation of coumaphos-hydrolysing bacteria. Lett Appl Microbiol 34(4):263-268. PMID:1940156
• Kim K, Kim Y, Lee YT, Hammock BD, Lee H. 2002. Development of an enzyme-linked immunosorbent assay for the organophosphorus insecticide bromophos-ethyl. J Agric Food Chem 50(23):6675-6682. PMID:12405760
• Lee H, Shan G, Watanabe T, Stoutamire DW, Gee SJ, Hammock BD. 2002. Enzyme-linked immunosorbent assay for the pyrethroid deltamethrin. J Agric Food Chem 50(20):5526-5532. PMID:12236674
• Leppert VJ, Harvey AS, McCool GD, Quinlan FT, Feng J, Shan G, Stroeve P, Risbud SH, Hammock BD, Kennedy IM. 2002. Long-wavelength emitting nanocrystals for bioassay applications. In: Nanoscale Optics and Applications. Proceedings of SPIE, pp.110-121.
• Nagy SR, Denison MS. 2002. Specificity of nuclear protein binding to a CYP1A1 negative regulatory element. Biochem Biophys Res Commun 296(4):799-805. PMID:12200118
• Nagy SR, Liu G, Lam KS, Denison MS. 2002. Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry 41(3):861-868. PMID:11790108
• Park WC, Cho YA, Kim Y, Hammock BD, Lee YT, Lee H. 2002. Development of an enzyme-linked immunosorbent assay for the organophosphorus insecticide bromophos. Bulletin of the Korean Chemical Society 23(10):1399-1403.
• Rushing SR, Denison MS. 2002. The silencing mediator of retinoic acid and thyroid hormone receptors can interact with the aryl hydrocarbon (Ah) receptor but fails to repress Ah receptor-dependent gene expression. Arch Biochem Biophys 403(2):189-201. PMID:12139968
• Shelver WL, Shan G, Gee SJ, Stanker LH, Hammock BD. 2002. Comparison of immunoaffinity column recovery patterns of polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans on columns generated with different monoclonal antibody clones and polyclonal antibodies. Anal Chim Acta 457:199-209.
• Sugawara Y, Saito K, Ogawa M, Kobayashi S, Shan G, Sanborn JR, Hammock BD, Nakazawa H, Matsuki Y. 2002. Development of dioxin toxicity evaluation method in human milk by enzyme-linked immunosorbent assay--assay validation for human milk. Chemosphere 46(9-10):1471-1476. PMID:12002478
• Szurdoki F, Szekacs A, Le HM, Hammock BD. 2002. Synthesis of haptens and protein conjugates for the development of immunoassays for the insect growth regulator fenoxycarb. J Agric Food Chem 50(1):29-40. PMID:11754538
• Ziccardi MH, Gardner IA, Denison MS. 2002. Application of the luciferase recombinant cell culture bioassay system for the analysis of polycyclic aromatic hydrocarbons. Environ Toxicol Chem 21(10):2027-2033. PMID:12371477
• Zurek G, Gee SJ, Hammock BD. 2002. Development of an enzyme immunoassay for linoleic acid diols in urine. Anal Chim Acta 466(2):247-256.

2001

• Buchholz BA, Vogel JS, Gilman DS, Gee SJ, Hammock BD, Hui X, Wester RC, Maibach HI. 2001. Determining an occupational dermal exposure biomarker for atrazine through measurement of metabolites in human urine by HPLC-accelerator mass spectrometry. In: Toxicology of Skin. Taylor & Francis, Philadelphia, PA. pp.145-157.
• Lee JK, Ahn K, Park OS, Kang SY, Hammock BD. 2001. Development of an ELISA for the detection of the residues of the insecticide imidacloprid in agricultural and environmental samples. J Agric Food Chem 49(5):2159-2167. PMID:11368571
• Matveeva EG, Shan G, Kennedy IM, Gee SJ, Hammock BD. 2001. Homogeneous fluoroimmunoassay of a pyrethroid metabolite in urine. Anal Chim Acta 444:103-117.
• Shan G, Hammock BD. 2001. Development of sensitive esterase assays based on alpha-cyano-containing esters. Anal Biochem 299(1):54-62. PMID:11726184
• Shan G, Leeman WR, Gee SJ, Sanborn JR, Jones AD, Chang DP, Hammock BD. 2001. Highly sensitive dioxin immunoassay and its application to soil and biota samples. Anal Chim Acta 444:169-178.
• Staimer N, Gee SJ, Hammock BD. 2001. Development of a class-selective enzyme immunoassay for urinary phenolic glucuronides. Anal Chim Acta 444:27-36.
• Staimer N, Gee SJ, Hammock BD. 2001. Development of a sensitive enzyme immunoassay for the detection of phenyl-b-D-thioglucuronide in human urine. Fresenius J Anal Chem 369(3-4):273-279. PMID:11293704
• Watanabe T, Shan G, Stoutamire DW, Gee SJ, Hammock BD. 2001. Development of a class-specific immunoassay for the type I pyrethroid insecticides. Anal Chim Acta 444:119-129.

2000

• Kido H, Maquieira A, Hammock BD. 2000. Disc-based immunoassay microarrays. Anal Chim Acta 411(1-2):1-11.
• Lohse C, Jaeger LL, Staimer N, Sanborn JR, Jones AD, Lango J, Gee SJ, Hammock BD. 2000. Development of a class selective enzyme-linked immunosorbent assay for mercapturic acids in human urine. J Agric Food Chem 48(12):5913-5923. PMID:11312767
• Shan G, Huang W, Gee SJ, Buchholz BA, Vogel JS, Hammock BD. 2000. Isotope-labeled immunoassays without radiation waste. Proc Natl Acad Sci U S A 97(6):2445-2449. PMID:10706612
• Shan G, Leeman WR, Stoutamire DW, Gee SJ, Chang DP, Hammock BD. 2000. Enzyme-linked immunosorbent assay for the pyrethroid permethrin. J Agric Food Chem 48(9):4032-4040. PMID:10995309

1999

• Argiriadi MA, Morisseau C, Hammock BD, Christianson DW. 1999. Detoxification of environmental mutagens and carcinogens: Structure, mechanism, and evolution of liver epoxide hydrolase. Proc Natl Acad Sci U S A 96:10637-10642. PMID:10485878
• Buchholz BA, Fultz E, Haack KW, Vogel JS, Gilman DS, Gee SJ, Hammock BD, Hui X, Wester RC, Maibach HI. 1999. HPLC-accelerator MS measurement of atrazine metabolites in human urine after dermal exposure. Anal Chem 71(16):3519-3525. PMID:10464479
• Kido H, Szurdoki F, Gustin MS, Hammock BD. 1999. Chelate sensor method for mercury. In: Metals and Genetics. Kluwer Academic/Plenum Press, NY. pp.235-259.
• Morisseau C, Goodrow MH, Dowdy DL, Zheng J, Greene JF, Sanborn JR, Hammock BD. 1999. Potent urea and carbamate inhibitors of soluble epoxide hydrolases. Proc Natl Acad Sci U S A 96(16):8849-8854. PMID:10430859
• Shan G, Stoutamire DW, Gee SJ, Wengatz I, Hammock BD. 1999. Development of an immunoassay for the pyrethroid insecticide esfenvalerate. J Agric Food Chem 47(5):2145-2155. PMID:10552511
• Shan G, Wengatz I, Stoutamire DW, Gee SJ, Hammock BD. 1999. An enzyme-linked immunosorbent assay for the detection of esfenvalerate metabolites in human urine. Chem Res Toxicol 12(11):1033-1041. PMID:10563828
• Yazynina EV, Zherdev AV, Dzantiev BB, Izumrudov VA, Gee SJ, Hammock BD. 1999. Immunoassay techniques for detection of the herbicide simazine based on use of oppositely charged water-soluble polyelectrolytes. Anal Chem 71(16):3538-3543. PMID:10464482
• Yazynina EV, Zherdev AV, Dzantiev BB, Izumrudov VA, Gee SJ, Hammock BD. 1999. Microplate immunoassay technique using polyelectrolyte carriers: kinetic studies and application to detection of the herbicide atrazine. Anal Chim Acta 399(1-2):151-160.

1998

• Gilman DS, Gee SJ, Hammock BD, Vogel JS, Haack KW, Buchholz BA, Freeman SP, Wester RC, Hui X, Maibach HI. 1998. Analytical performance of accelerator mass spectrometry and liquid scintillation counting for detection of ¹⁴C-labeled atrazine metabolites in human urine. Anal Chem 70(16):3463-3469. PMID:9726169
• Goodrow MH, Hammock BD. 1998. Hapten design for compound-selective antibodies: ELISA's for environmentally deleterious small molecules. Anal Chim Acta 376(1):83-91.
• Harris AS, Wengatz I, Wortberg M, Kreissig SB, Gee SJ, Hammock BD. 1998. Development and application of immunoassays for biological and environmental monitoring. In: Effects of Multiple Impacts on Ecosystems. Lewis Publishers, Chelsea, MI. pp.135-153.
• Jaeger LL, Jones AD, Hammock BD. 1998. Development of an enzyme-linked immunosorbent assay for atrazine mercapturic acid in human urine. Chem Res Toxicol 11(4):342-352. doi:10.1021/tx9701844 PMID:9548805
• Marco M, Gee SJ, Hammock BD. 1998. Determination of 1-naphthol in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C.9.1-2C.9.11.
• Marco M, Gee SJ, Hammock BD. 1998. Determination of carbaryl in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C8.1-2C8.15.
• Mitchell AE, Zheng J, Hammock BD, Lo Bello M, Jones AD. 1998. Structural and functional consequences of haloenol lactone inactivation of murine and human glutathione S-transferase. Biochemistry 37(19):6752-6759. PMID:9578559
• Reimer GJ, Gee SJ, Hammock BD. 1998. Comparison of a time-resolved fluorescence immunoassay and an enzyme-linked immunosorbent assay for the analysis of atrazine in water. J Agric Food Chem 46(8):3353-3358.
• Sanborn JR, Gee SJ, Gilman DS, Sugawara Y, Jones AD, Rogers JM, Szurdoki F, Stanker LH, Stoutamire DW, Hammock BD. 1998. Hapten synthesis and antibody development for polychlorinated dibenzo-p-dioxin immunoassays. J Agric Food Chem 46:2407-2416.
• Sugawara Y, Gee SJ, Sanborn JR, Gilman DS, Hammock BD. 1998. Development of a highly sensitive enzyme-linked immunosorbent assay based on polyclonal antibodies for the detection of polychlorinated dibenzo-p-dioxins. Anal Chem 70(6):1092-1099. PMID:9530001
• Wengatz I, Stoutamire DW, Gee SJ, Hammock BD. 1998. Development of an enzymelinked immunosorbent assay for the detection of the pyrethroid insecticide fenpropathrin. J Agric Food Chem 46(6):2211-2221.

1997

• Jones G, Wortberg M, Rocke DM, Hammock BD. 1997. Immunoassay of cross-reacting analytes. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.331-342.
• Kido H, Goodrow MH, Griffeth V, Lucas AD, Gee SJ, Hammock BD. 1997. Development of an enzyme-linked immunosorbent assay for the detection of hydroxytriazines. J Agric Food Chem 45(2):414-424.
• Moghaddam MF, Grant DF, Cheek JM, Greene JF, Williamson K, Hammock BD. 1997. Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase. Nat Med 3(5):562-566. PMID:9142128
• Schutz S, Wengatz I, Goodrow MH, Gee SJ, Hummel HE, Hammock BD. 1997. Development of an enzyme-linked-immunosorbent assay for azadirachtins. J Agric Food Chem 45(6):2363-2368.
• Swamy AR, Danesvar MI, Evans, III L, Strekowski L, Narayanan N, Szurdoki F, Wengatz I, Hammock BD, Patonay G. 1997. Near-infrared fluorescent immunoassays: A novel approach to environmental analysis. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.141-161.
• Szurdoki F, Kido H, Hammock BD. 1997. Rapid mercury assays. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.38-48.
• Zheng J, Cho M, Jones AD, Hammock BD. 1997. Evidence of quinone metabolites of naphthalene covalently bound to sulfur nucleophiles of proteins of murine clara cells after exposure to naphthalene. Chem Res Toxicol 10(9):1008-1014. PMID:9305583

1996

• Grant DF, Greene JF, Pinot F, Borhan B, Moghaddam MF, Hammock BD, McCutchen B, Ohkawa H, Luo G, Guenthner TM. 1996. Development of an in situ toxicity assay system using recombinant baculoviruses. Biochem Pharmacol 51(4):503-515. PMID:8619897
• Jones G, Wortberg M, Hammock BD, Rocke DM. 1996. A procedure for the immunoanalysis of samples containing one or more members of a group of cross-reacting analytes. Anal Chim Acta 336(1-3):175-183.
• Jones G, Wortberg M, Kreissig SB, Hammock BD, Rocke DM. 1996. Application of the bootstrap to calibration experiments. Anal Chem 68(5):763-770. PMID:8779441
• Linde CD, Gee SJ, Goh KS, Hsu JC, Hammock BD, Barry TA, Weaver DJ. 1996. Regulatory application of ELISA: compliance monitoring of bromacil in soil. Bull Environ Contam Toxicol 57(2):264-269. PMID:8661908
• Szurdoki F, Jaeger LL, Harris AS, Kido H, Wengatz I, Goodrow MH, Szekacs A, Wortberg M, Zheng J, Stoutamire DW, Sanborn JR, Gilman DS, Jones AD, Gee SJ, Choudary P, Hammock BD. 1996. Rapid assays for environmental and biological monitoring. J Environ Sci Health B 31(3):451-458. PMID:8642182
• Wengatz I, Harris AS, Gilman DS, Wortberg M, Kido H, Szurdoki F, Goodrow MH, Jaeger LL, Stoutamire DW, Sanborn JR, Gee SJ, Hammock BD. 1996. Recent developments in immunoassays and related methods for the detection of xenobiotics. In: Environmental Immunochemical Methods, Perspectives and Applications. ACS Symposium Series No. 646, American Chemical Society, Washington, DC. pp.110-126.
• Wortberg M, Goodrow MH, Gee SJ, Hammock BD. 1996. Immunoassay for simazine and atrazine with low cross-reactivity for propazine. J Agric Food Chem 44(8):2210-2219.
• Wortberg M, Jones G, Kreissig SB, Rocke DM, Gee SJ, Hammock BD. 1996. An approach to the construction of an immunoarray for differentiating and quantitating cross reacting analytes. Anal Chim Acta 319(3):291-303.
• Zheng J, Hammock BD. 1996. Development of polyclonal antibodies for detection of protein modification by 1,2-naphthoquinone. Chem Res Toxicol 9(5):904-909. PMID:8828928
• Zheng J, Mitchell AE, Jones AD, Hammock BD. 1996. Haloenol lactone is a new isozyme-selective and active site-directed inactivator of glutathione S-transferase. J Biol Chem 271(34):20421-20425. PMID:8702779

1995

• Borhan B, Jones AD, Pinot F, Grant DF, Kurth M, Hammock BD. 1995. Mechanism of soluble epoxide hydrolase. Formation of An a-hydroxy ester-enzyme intermediate through Asp-333. J Biol Chem 270(45):26923-26930. PMID:7592938
• Gee SJ, Hammock BD, Skerritt JH. 1995. Diagnostics for plant agrochemicals--a meeting of chemistry and immunoassay. In: New Diagnostics in Crop Sciences. CAB International, Oxon, United Kingdom. pp.243-276.
• Gee SJ, Lucas AD, Hammock BD. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Proceedings of the NATO (North Atlantic Treaty Organisation) Workshop on Methods of Pesticide Exposure Assessment. Ottawa, Canada.
• Gee SJ, Lucas AD, Hammock BD. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Methods of Pesticide Exposure Assessment. Plenum Press, NY. pp.143-155.
• Goodrow MH, Sanborn JR, Stoutamire DW, Gee SJ, Hammock BD. 1995. Strategies for immunoassay hapten design. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.119-139.
• Hammock BD, Gee SJ. 1995. Impact of emerging technologies on immunochemical methods for environmental analysis. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.1-19.
• Harris AS, Lucas AD, Kramer PM, Marco M, Gee SJ, Hammock BD. 1995. Use of immunoassay for the detection of urinary biomarkers of exposure. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.217-235.
• Jones G, Wortberg M, Kreissig SB, Hammock BD, Rocke DM. 1995. Sources of experimental variation in calibration curves for enzyme-linked immunosorbent assay. Anal Chim Acta 313:197-207.
• Kreissig SB, Ward VK, Hammock BD, Choudary P. 1995. Nucleotide sequence of the variable region of the heavy and light chains of a monoclonal lgG antibody reactive to herbicides, terbutryn and prometryn. DNA Seq 6:51-54. PMID:8746462
• Kreissig SB, Ward VK, Hammock BD, Choudary P. 1995. Sequence analysis of individual chains of antibodies to triazine herbicides. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.31-49.
• Lucas AD, Gee SJ, Hammock BD, Seiber JN. 1995. Integration of immunochemical methods with other analytical techniques for pesticide residue determination. J AOAC Int 78(3):585-591. PMID:7756872
• Lucas AD, Goodrow MH, Seiber JN, Hammock BD. 1995. Development of an ELISA for the N-dealkylated s-triazines: Application to environmental and biological samples. Anal Chim Acta 7:227-241.
• Marco M, Chiron S, Gascon J, Hammock BD, Barcelo D. 1995. Validation of two immunoassay methods for environmental monitoring of carbaryl and 1-naphthol in ground water samples. Anal Chim Acta 311(3):319-329.
• Schneider P, Gee SJ, Kreissig SB, Harris AS, Kramer PM, Marco M, Lucas AD, Hammock BD. 1995. Troubleshooting during the development and use of immunoassays for environmental monitoring. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.103-122.
• Sundaram KM, Sundaram A, Gee SJ, Harrison RO, Hammock BD. 1995. Enzyme-linked immunosorb and assay for quantification of Bacillus thuringiensis var. kurstaki crystaline protein in commerical formulations, in relation to total protein content and insecticidal activity. In: Pesticide Formulations and Applicaiton Systems, 14^th Volume. American Society for Testing and Materials, Philadelphia, PA.
• Szekacs A, Hammock BD. 1995. Development of an enzyme-linked immunosorbent assay for the detection of the triazole fungicide myclobutanil. J Agric Food Chem 43(8):2083-2091.
• Szekacs A, Jung F, Hammock BD. 1995. Chemical modification of haptens: Selective amino group protection by chromophores for an immunoassay for aminotriazoles. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.65-75.
• Szurdoki F, Bekheit HK, Marco M, Goodrow MH, Hammock BD. 1995. Important factors in hapten design and enzyme-linked immunosorbent assay development. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.39-63.
• Szurdoki F, Kido H, Hammock BD. 1995. Development of assay for analysis of Hg²⁺ based on sulfur-containing ligands. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.248-264.
• Szurdoki F, Kido H, Hammock BD. 1995. Development of rapid mercury assays. Synthesis of sulfur-and mercury-containing conjugates. Bioconjug Chem 6(2):145-149. PMID:7599258
• Tsuruda LS, Lame MW, Jones AD. 1995. Formation of epoxide and quinone protein adducts in B6C3F1 mice treated with naphthalene, sulfate conjugate of 1,4- dihydroxynaphthalene and 1,4-naphthoquinone. Arch Toxicol 69(6):362-367. PMID:7495373
• Tsuruda LS, Lame MW, Jones AD. 1995. Metabolism of [¹⁴C]naphthalene in the B6C3F1 murine isolated perfused liver. Drug Metab Dispos 23(1):129-136. PMID:7720516
• Ward VK, Hammock BD, Maeda S, Choudary P. 1995. Development and application of recombinant antibodies to pesticide residue analysis. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.197-216.
• Ward VK, Kreissig SB, Hammock BD, Choudary P. 1995. Generation of an expression library in the baculovirus expression vector system. J Virol Methods 53(2-3):263-272. PMID:7673393
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